Red flag diagnoses as predictors of ATTR-CM diagnosis (limited to red flags significant at the 5% level)
| Red flag diagnosis* | OR | P value | 95% CI |
| Carpal tunnel syndrome (unilateral and bilateral) | 6.718 | <0.001 | 5.542 to 8.143 |
| Spinal stenosis | 2.702 | <0.001 | 2.092 to 3.489 |
| Irritable bowel syndrome | 2.455 | 0.020 | 1.150 to 5.240 |
| Supraventricular tachycardia | 1.897 | 0.024 | 1.087 to 3.309 |
| Atrioventricular and left bundle branch block | 1.626 | 0.002 | 1.195 to 2.211 |
| Atrial fibrillation and flutter | 1.214 | 0.008 | 1.053 to 1.400 |
*The multivariate regression model included all red flags and the results were controlled for patients’ age, sex and comorbidity index. The results for all covariates are found in online supplemental material.
ATTR-CM, transthyretin amyloid cardiomyopathy.