Table 1

Characteristics of the recruited participants

P value
Age, years* median (IQR)53.0 (46.0–59.0)59.0 (51.5–66.5)<0.0001
Highest total cholesterol, mmol/L
median (IQR)
7.4 (6.6–8.0)7.7 (6.8–8.3)0.023
Median highest Low-density lipoprotein cholesterol, mmol/L median (IQR)5.0 (4.0–5.3)5.1 (4.3–5.7)0.047
Family history of premature coronary heart disease†41 (51.3)89 (49.4)0.788
Statin prescribed24 (30%)42 (23%)0.254
FAMCAT 1 probability of FH, median (IQR)0.047 (0.20–0.091)0.010 (0.003–0.217)<0.0001
Fulfils Simon-Broome possible FH criteria‡21 (26.3%)59 (32.8%)0.293
  • P value, Mann-Whitney U test for continuous variables and χ2 test for categorical variables.

  • *Age at time of recruitment into the study.

  • †Premature defined as coronary heart disease <50 years in second-degree relative or <60 years in first-degree relative.

  • ‡Simon-Broome possible FH criteria defined as having a total cholesterol >7.5 mmol/L or LDL-C >4.9 mmol/L and a family history of premature coronary heart disease.

  • FAMCAT, Familial Hypercholesterolaemia Case Ascertainment Tool; FH, familial hypercholesterolaemia.