Time to hard event univariate models, idiopathic and hereditary pulmonary arterial hypertension only
| Covariate | HR | Lower CI | Upper CI | P value | AIC |
| Ees/Ea_(Takeuchi) | 4.34 | 3.6 | 10.0 | 0.001 | 128 |
| Ees/Ea_(Kind) | 2.17 | 1.3 | 3.6 | 0.003 | 135 |
| PVRi, Pa s/m³ | 1.88 | 1.4 | 2.5 | <0.001 | 129 |
| mPAP, mm Hg | 2.78 | 1.8 | 4.3 | <0.001 | 135 |
| RVCI, L/min/m2 | 0.77 | 0.43 | 1.4 | 0.385 | 142 |
| Pes (mm Hg) | 2.57 | 1.6 | 4.1 | <0.001 | 128 |
| RVSV | 0.63 | 0.35 | 1.4 | 0.12 | 139 |
| Pmax_(Takeuchi) | 1.13 | 0.77 | 1.7 | 0.529 | 143 |
| Pmax_(Kind) | 1.56 | 1.002 | 2.4 | 0.049 | 139 |
Data are expressed as Cox proportional hazard regression estimate and HR with CIs, unless otherwise noted. Models are compared using Akaike information criterion (AIC).
Ees/Ea_(Kind), vascular–ventricular coupling ratio Kind method; Ees/Ea_(Takeuchi), vascular–ventricular coupling Takeuchi method.
Bold p-values indicate significance.
Ees/Ea _(Kind), vascular–ventricular coupling ratio Kind method; Ees/Ea _(Takeuchi), vascular–ventricular coupling Takeuchi method; mPAP, mean pulmonary arterial hypertension; Pes, end-systolic pressure; Pmax, maximum theoretical pressure; PVRi, indexed pulmonary vascular resistance; RVCI, right ventricular cardiac index; RVSV, right ventricular stroke volume.