Outputs from multiple Mendelian randomisation (MR) methods using genetic variants associated with body mass index (BMI) as instrument variables to test for genetic evidence of an aetiological relationship between BMI and red cell distribution width
Method | Estimate | SE | P value |
Simple median | 0.5 | 0.13 | <0.001 |
Weighted median | 0.55 | 0.14 | <0.001 |
Inverse weighted median | 0.52 | 0.09 | <0.001 |
MR-egger | 0.5 | 0.22 | 0.025 |
(MR-egger intercept) | 0.001 | 0.006 | 0.91 |
All models used random-effects modelling.