Table 2

Outputs from multiple Mendelian randomisation (MR) methods using genetic variants associated with body mass index (BMI) as instrument variables to test for genetic evidence of an aetiological relationship between BMI and red cell distribution width

Method	Estimate	SE	P value
Simple median	0.5	0.13	<0.001
Weighted median	0.55	0.14	<0.001
Inverse weighted median	0.52	0.09	<0.001
MR-egger	0.5	0.22	0.025
(MR-egger intercept)	0.001	0.006	0.91

All models used random-effects modelling.