Table 2

All-cause mortality according to birth cohort and to age at diagnosis in patients with isolated PS and controls

PS, totalControls, totalRisk of mortality
No of deaths among patients/total no of patients (%)No of deaths among controls/total no of controls (%)HR (95% CI)P value
Death events, nMortality rate per 100 000 person-yearsDeath events, nMortality rate per 100 000 person-years
All88/3910 (2.3)192/38 770 (0.5)4.67 (3.61 to 5.99)<0.0001
Birth period
 1970–197915149.2 (83.5–246.1)3937.3 (26.5–51.0)4.02 (2.14 to 7.16)<0.0001
 1980–198923171.0 (108.4–256.7)4834.5 (25.4–45.7)4.98 (2.97 to 8.11)<0.0001
 1990–199324137.2 (87.9–204.2)4625.8 (18.9–34.4)5.35 (3.21 to 8.68)<0.0001
 2000–20091484.9 (46.4–142.5)3320.1 (13.9–28.3)4.25 (2.19 to 7.79)<0.0001
 2010–201612246.9 (127.6–431.3)2654.0 (35.2–79.1)4.61 (2.23 to 8.97)<0.0001
Age at registration, years
0–1 year718944.7 (6985.9–11 282.6)64813.4 (626.4–1038.7)10.99 (7.84 to 15.45)<0.0001
1–10 years6123.2 (45.2–268.1)52107.5 (80.3–140.9)1.17 (0.45 to 2.53)0.751
 >10 years1179.2 (39.5–141.7)7654.7 (43.1–68.5)1.47 (0.73 to 2.64)0.249
  • PS, pulmonary stenosis.;