Table 2

Laboratory testing and outcomes stratified by COVID-19 status

COVID-19-negativeCOVID-19-positiveP value
Admission lab values, median (IQR)
 BUN (mg/dL)25 (20–44)24.5 (15–45)0.65
 Creatinine (mg/dL)1.37 (0.92–2.02)1.42 (0.91–1.94)0.74
 GFR (mg/min/1.73 m2)31.5 (23.5–48.0)46 (30–60)0.09
 Sodium (mmol/L)136 (134.5–139.0)136.5 (134.8–139.0)0.82
 Potassium (mmol/L)4.2 (3.85–4.65)4.2 (3.9–4.5)0.66
 Bicarbonate (mmol/L)21 (19–24)23 (20–25)0.46
 Glucose (mg/dL)136 (110.4–232.5)131 (109.5–169.0)0.27
 WBC (×109/L)10.61 (8.25–14.52)6.1 (4.6–8.4)0.002
 Haemoglobin (g/dL)12.5 (10.95–14.25)12.9 (10.9–14.2)0.67
 Haematocrit (%)37.8 (33.6–43.35)39.3 (35.0–42.5)0.78
 Platelets (k/uL)206 (175.5–250)186.5 (139.8–234.8)0.19
 Albumin (g/dL)3.8 (3.4–4.0)3.5 (3.1–3.8)0.08
 AST (U/L)30 (24.5–64.0)39.5 (31.9–74.5)0.22
 ALT (U/L)20 (17.5–37.0)26.5 (19–41)0.60
 CRP (mg/L)6.1 (3.6–13.3)10.4 (5.0–16.9)0.41
 Lactate (mmol/L)2.8 (1.6–3.95)1.6 (1.2–2.3)0.02
 Procalcitonin (ng/mL)1.39 (0.75–2.92)0.34 (0.18–0.66)0.04
 IL-6 (pg/mL)115.6 (67.8–19 834.25)62 (20.5–120.1)0.39
 NT Pro-BNP (pg/mL)3712 (305–9787)567 (181–2771)0.11
 Troponin T (ng/L)0.13 (0.04–0.4)0.03 (0.01–0.05)0.001
 Hs-troponin (ng/L)72 (65.0–268.5)33 (14–56)0.02
 Creatine kinase (U/L)134.5 (81.25–238)230 (98–461)0.31
 CK-MB (ng/mL)3.3 (2.3–26.65)3.8 (2.2–4.5)0.56
 D-dimer (ug/mL)2840 (2150–8890)1250 (610–3300)0.08
 Fibrinogen (mg/dL)509 (343–679)541 (434.5–667.5)0.64
 Ferritin (ug/L)294.5 (167.62–506.35)704 (459–1470)0.13
Hospitalisation characteristics
 Hospitalisation required (%)23 (100)56 (100)>0.99
 Pneumonia on CXR (%)5 (21.7)39 (69.6)<0.001
 Oxygen therapy14 (60.9)50 (89.3)0.009
 ICU required22 (95.7)43 (76.8)0.10
 ICU length of stay (mean±SD)5.0±4.115.9±11.7<0.001
 NIPPV (%)2 (8.7)7 (12.5)0.92
 Mechanical ventilation (%)9 (39.1)33 (58.9)0.18
 Ventilation length (days) (mean±SD)6±5.913.9±11.80.06
 Prone ventilation (%)0 (0)12 (21.4)0.04
 Dialysis2 (8.7)16 (28.6)0.11
 Shock (%)13 (56.5)31 (55.4)>0.99
 Vasoactive drips (%)16 (69.6)33 (58.9)0.53
 Mechanical circulatory support3 (13)4 (7.1)0.69
 Death (%)8 (34.8)14 (25)0.55
  • ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CK-MB, creatine kinase myocardial band; CRP, C reactive protein; CXR, chest X-ray; GFR, glomerular filtration rate; ICU, intensive care unit; IL-6, interleukin-6; NIPPV, non-invasive positive-pressure ventilation; NT Pro-BNP, N-terminal pro b-type natriuretic peptide; WBC, white blood cell.