Table 4

Multivariable linear regression for the association between sedentary behaviour and echocardiogram measures

OutcomeModel 1Model 2Model 3
LVMI, g/m2.70.0626*0.04850.0433
RWT, ratio0.0000−0.00020.0000
LAVI, mL/m2−0.0066−0.0066−0.0035
EF, %−0.0025−0.00050.0025
E/e′, ratio0.0144−0.0074−0.0341
GLS, %0.00410.00350.0014
GCS, %−0.0377−0.0390−0.0413
SV, mL0.0073−0.00390.0001
RV peak S, cm/s0.00900.00750.0068
RV FAC0.00010.00010.0002
TRV max, cm/s−0.0457−0.0459−0.0330
TAPSE, cm−0.0010−0.0011−0.0010
  • M1: demographics (age and sex).

  • M2: M1+systolic blood pressure, antihypertensive med use.

  • M3: M2+other cardiovascular disease modifiable factors (diabetes mellitus, current smoking and high-density lipoprotein).

  • Values are per 10 min/day of sedentary behaviour.

  • *P value <0.01.

  • E, peak early diastolic transmitral inflow velocities; EDV, end diastolic volume; e′, average of mitral early diastolic septal and lateral annular velocities; EF, ejection fraction; GCS, global circumferential strain; GLS, global longitudinal strain; LAVI, left atrial volume index; LVMI, left ventricular mass index; M, model; RV, right ventricular; RV FAC, RV fractional area change; RWT, relative valve thickness; SV, stroke vol; TAPSE, tricuspid annular plane systolic excursion; TRV, tricuspid regurgitation velocity.