Comparison of thrombin generation-, surrogate platelet activity and hepatic dysfunction outcome between the major-bleeding and minor-bleeding group
| Thrombing generation | Major bleeding | Minor bleeding | P value |
| Mean (SD) | Mean (SD) | ||
| ETP | 1011.06 (±138.44) | 1218.25 (±74.33) | 0.109 |
| Peak | 252.86 (±90.91) | 321.81 (±55.06) | 0.248* |
| Time to peak | 4.75 (±0.35) | 4.41 (±0.32) | 0.374* |
| Velocity index | 117.00 (±58.79) | 158.06 (±32.50) | 0.373 |
| Alpha-2 level | 8.91 (±4.11) | 19.84 (±5.63) | 0.083* |
| Platelet activity markers | |||
| P-selectin level | 32.642 (±4.624) | 29.912 (±5.699) | 0.564* |
| PF4 level | 130.115 (±0) | 351.351 (±312.875) | 0.48* |
| Hepatic dysfunction | |||
| Fibro-scan | 29.3 (±17.5) | 21.3 (±8.5) | 0.564* |
| Fibro-test score | 0.471 (±0) | 0.692 (±0.24) | 0.587 |
| MELD-XI score | 10.05 (±4.74) | 9.23 (±2.52) | 0.811 |
*Differences between groups were anaylysed using an independent-samples t-test. If the normality assumption was severely violated, a Mann-Whitney U test was used. Values marked by an asterisk were analysed by use of the Mann-Whitney U test.
ETP, endogenous thrombin potential; MELD-XI, model for end-stage liver disease excluding international normalised ratio; PF4, platelet factor 4.