Correlation of markers for hepatic dysfunction with thrombin generation and platelet activity markers
| ETP | Lag time | Peak | Time to peak | Velocity index | Start of tail | Alpha-2 level | P-selectin level | PF4 level | ||
| MELD-XI score | Correlation | 0.073 | 0.131 | 0.023 | 0.198* | −0.051 | 0.171* | −0.065 | −0.088 | −0.127 |
| P value | 0.540 | 0.142 | 0.786 | 0.025 | 0.669 | 0.045 | 0.441 | 0.308 | 0.189 | |
| Median KPA | Correlation | −0.138 | 0.125 | −0.174* | 0.124 | −0.177* | 0.127 | −0.155 | −0.010 | −0.055 |
| P value | 0.101 | 0.160 | 0.038 | 0.154 | 0.035 | 0.131 | 0.065 | 0.907 | 0.576 | |
| Fibrotest score | Correlation | −0.174 | 0.090 | −0.108 | 0.156 | −0.218 | 0.154 | 0.083 | −0.094 | −0.201* |
| P value | 0.188 | 0.340 | 0.226 | 0.093 | 0.097 | 0.087 | 0.353 | 0.298 | 0.046 | |
*Correlations between variables were analysed using a Pearson’s r. If the normality assumption of either variable was violated, a Kendall’s tau coefficient was used to analyse correlations between variables. Values marked by an asterisk were analysed by use of the Kendall’s tau coefficient.
ETP, endogenous thrombin potential; MELD-XI, model for end-stage liver disease excluding international normalised ratio; PF4, platelet factor 4.