Event rates and crude and adjusted HRs for the composite outcome by visually estimated coronary artery calcium
| Outcomes, n (%) | VECAC ≤10 N=416 | VECAC 11–400 N=74 | VECAC >400 N=118 |
| Composite endpoint (total events=103) | |||
| Event rate and 95% CI (per 100 person-years) | 2.2 (1.6 to 3.0) | 5.7 (3.5 to 9.2) | 9.5 (7.1 to 12.7) |
| Crude model HR (95% CI) | Ref | 2.59 (1.47 to 4.56) | 4.32 (2.82 to 6.60) |
| Multivariable adjusted model 1 HR (95% CI) | Ref | 2.25 (1.25 to 4.07) | 3.34 (2.06 to 5.43) |
| Multivariable adjusted model 2 HR (95% CI) | Ref | 2.25 (1.24 to 4.08) | 3.05 (1.87 to 4.98) |
Model 1 covariates include age, sex, race, high-density cholesterol, total cholesterol, systolic blood pressure, history of diabetes mellitus, current smoking and use of blood pressure medication.
Model 2 covariates additionally include myocardial perfusion imaging (fixed or reversible defects) and coronary flow reserve.
VECAC, visually estimated coronary artery calcium.