Characteristics of patients with or without POCD 6 months after CABG
| No POCD (n=88) | POCD (n=43) | P value | |
| Baseline characteristics | |||
| Sex (female) | 10 (11) | 5 (12) | >0.99 |
| Age (years), mean (SD) | 63 (9.2) | 67 (9.0) | 0.040 |
| BMI (kg/m2) | 0.29 | ||
| <25 | 18 (20) | 13 (30) | |
| 25–30 | 49 (56) | 18 (42) | |
| >30 | 21 (24) | 12 (28) | |
| Log EuroSCORE I, median (IQR) In groups | 2.6 (1.5–4.4) | 3.6 (2.1–5.3) | 0.72 |
| <10% | 83 (94) | 40 (93) | 0.15 |
| 10%–20% | 5 (6.0) | 3 (7.0) | |
| EuroSCORE II, median (IQR) | 1.5 (1.1–2.2) | 1.5 (1.1–2.5) | 0.71 |
| Diabetes mellitus | 20 (2.3) | 9 (20.9) | 0.79 |
| Pulmonary disease | 7 (8.0) | 7 (16.3) | 0.23 |
| Arterial vascular disease | 4 (4.5) | 3 (7.0) | 0.68 |
| Renal disease | 8 (9.1) | 5 (11.6) | 0.76 |
| LVEF | 0.54 | ||
| >50% | 58 (66) | 33 (36) | |
| 30%–50% | 29 (33) | 10 (23) | |
| <30% | 1 (1.1) | 0 (0.0) | |
| Education level | 0.046 | ||
| Low | 27 (31) | 9 (21) | |
| Moderate | 39 (44) | 14 (33) | |
| High | 22 (25) | 20 (46) | |
| Baseline PCS, mean (SD) | 65 (20) | 63 (19) | 0.46 |
| Baseline MCS, mean (SD) | 71 (20) | 73 (21) | 0.51 |
| Cognitive test results, mean (SD) | |||
| DET | 101 (6.7) | 103 (5.3) | 0.24 |
| IDN | 100 (4.9) | 101 (4.9) | 0.69 |
| OCL | 104 (8.7) | 104 (8.4) | 0.71 |
| ONB | 98 (5.6) | 98 (6.1) | 0.49 |
| Operative characteristics | |||
| Surgical time,* mean (SD) | 257 (46) | 249 (33) | 0.24 |
| CPB time,* mean (SD) | 108 (32) | 101 (24) | 0.21 |
| Cross-clamp time,* mean (SD) | 66 (23) | 61 (22) | 0.21 |
| Postoperative characteristics | |||
| Delirium | 1 (1.1) | 5 (12) | 0.015 |
| Atrial fibrillation | 9 (10) | 5 (12) | >0.99 |
| Myocardial infarction | 1 (1.1) | 0 (0.0) | >0.99 |
| Surgical re-exploration | 2 (2.3) | 0 (0.0) | >0.99 |
| Deep sternal wound infection | 2 (2.3) | 0 (0.0) | >0.99 |
| ICU stay†, median (IQR) | 21 (18–25) | 21 (17–23) | 0.25 |
| Discharge destination | 0.99 | ||
| Home | 63 (72) | 31 (72) | |
| Other hospital | 12 (14) | 6 (14) | |
| Rehabilitation centre | 12 (14) | 6 (14) | |
| Nursing home | 0 (0.0) | 0 (0.0) | |
Values are presented as n (%) unless otherwise indicated.
*Surgical time, CPB time and cross-clamp time in minutes.
†ICU stay in hours.
BMI, Body Mass Index; CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; DET, detection task; ICU, intensive care unit; IDN, identification task; LVEF, left ventricular ejection fraction; MCS, Mental Component Score; OCL, one card learning task; ONB, one back task; PCS, Physical Component Score; POCD, postoperative cognitive dysfunction.