Table 4

Cox proportional hazard models for adverse events

Exercise type	Parameter	Univariable		Adjusted by MAGGIC score
Exercise type	Parameter	HR (95% CI)	P value	HR (95% CI)	P value
Ergometer-ESE	High Δ LVEF	0.85 (0.40 to 1.81)	0.68	0.85 (0.40 to 1.80)	0.67
	High Δ GLS	0.33 (0.14 to 0.77)	0.010	0.39 (0.16 to 0.91)	0.030
	Increased MR grade	0.52 (0.25 to 1.11)	0.09	0.55 (0.26 to 1.18)	0.13
	High Δ sPAP	0.65 (0.28 to 1.48)	0.31	0.65 (0.29 to 1.49)	0.31
Handgrip-ESE	High Δ LVEF	1.52 (0.70 to 3.31)	0.29	1.45 (0.67 to 3.17)	0.35
	High Δ GLS	1.05 (0.50 to 2.20)	0.90	1.04 (0.50 to 2.20)	0.91
	Increased MR grade	0.82 (0.33 to 2.04)	0.68	0.60 (0.23 to 1.58)	0.30
	High Δ sPAP	1.03 (0.46 to 2.31)	0.93	1.00 (0.44 to 2.24)	0.99

Bold type indicates statistical significance (p<0.05).
ESE, exercise stress echocardiography; GLS, global longitudinal strain; LVEF, left ventricular ejection fraction; MAGGIC, Meta-Analysis Global Group In Chronic heart failure; MR, mitral regurgitation; sPAP, systolic pulmonary artery pressure.