Patient characteristics
| Parameter | |
| Age, years old | 68 (58–78) |
| Male, n (%) | 37 (69.8) |
| Body mass index (kg/m2) | 23.0 (20.1–24.7) |
| Systolic blood pressure, mm Hg | 110 (99–124) |
| Diastolic blood pressure, mm Hg | 69 (64–75) |
| Heart rate, /min | 69 (60–77) |
| Medical history | |
| Ischaemic cardiomyopathy, n (%) | 24 (45.3) |
| COPD, n (%) | 18 (34.0) |
| Diabetes, n (%) | 31 (58.5) |
| Heart failure severity | |
| NYHA class ≥III, n (%) | 18 (34.0) |
| B-type natriuretic peptide, pg/mL | 284 (186–520) |
| MAGGIC score | 30 (23–33) |
| Echocardiography | |
| Interventricular septum, mm | 10 (8–11) |
| LV diastolic diameter, mm | 59 (52–66) |
| LV systolic diameter, mm | 50 (42–60) |
| Left atrial diameter, mm | 44 (39–49) |
| LV ejection fraction, % | 26 (16–35) |
| Mitral E velocity, cm/s | 81 (66–102) |
| Tissue Doppler e', cm/s | 4.6 (3.5–5.7) |
| E/e' | 16.0 (12.3–24.6) |
| Right atrial pressure, mm Hg | 8 (3–8) |
| Systolic PAP, mm Hg | 33 (29–39) |
| GLS, % (absolute value) | 9.2 (6.0–14.0) |
| MR volume, mL | 20 (14–26) |
| Mitral EROA, cm2 | 0.12 (0.10–0.17) |
| MR/LA area ratio | 0.21 (0.12–0.27) |
| Mitral valve tenting height, mm | 9.3 (8.0–10.9) |
| MR grade, n (%) | |
| Mild | 26 (49.1) |
| Moderate | 19 (35.8) |
| Moderate-to-severe | 7 (13.2) |
| Severe | 1 (1.9) |
COPD, chronic obstructive pulmonary disease; EROA, effective regurgitant orifice; GLS, global longitudinal strain; LA, left atrium; LV, left ventricular; MAGGIC, Meta-Analysis Global Group In Chronic heart failure; MR, mitral regurgitation; NYHA, New York Heart Association; PAP, pulmonary artery pressure.