Variable | No events* (n=615) | Composite outcome* (n=224) | Crude OR (95% CI) | Adjusted OR (95% CI) | P value |
History of CV disease | 136 (22%) | 141 (63%) | 6.0 (4.3 to 8.4) | 2.4 (1.6 to 3.5) | <0.001 |
Age (per 10 years) | 60 (50–75) | 82 (74–88) | 2.3 (2.0 to 2.7) | 2.2 (1.9 to 2.6) | <0.001 |
Male gender | 321 (52%) | 132 (59%) | 1.3 (.97 to 1.8) | 1.6 (1.1 to 2.3) | 0.02 |
Lung opacity/infiltration | 100 (16%) | 51 (23%) | 1.5 (1.0 to 2.2) | 1.9 (1.2 to 3) | 0.01 |
Hypertension | 249 (40%) | 143 (64%) | 2.6 (1.9 to 3.6) | 0.87 (0.58 to 1.3) | 0.50 |
Obesity† | 153/544 (28%) | 53/215 (25%) | 0.84 (0.58 to 1.2) | – | – |
Dyslipidaemia | 131 (21%) | 74 (33%) | 1.8 (1.3 to 2.6) | 0.89 (0.58 to 1.3) | 0.57 |
Diabetes | 105 (17%) | 64 (29%) | 1.9 (1.4 to 2.8) | 1.5 (0.95 to 2.3) | 0.08 |
Smoking | 26 (4%) | 11 (5%) | 1.2 (0.55 to 2.3) | 1.5 (0.6 to 3.4) | 0.37 |
COPD | 22 (4%) | 27 (12%) | 3.7 (2.1 to 6.7) | 2.1 (1.1 to 4.2) | 0.03 |
OSA | 46 (7%) | 23 (10%) | 1.4 (0.82 to 2.4) | 1.4 (0.7 to 2.6) | 0.28 |
*Data are n (%) or median (Q1–Q3).
†Missing BMI: n=80.
BMI, body mass index; COPD, chronic obstructive pulmonary disease; CV, cardiovascular; MACE, major adverse cardiovascular event; OSA, obstructive sleep apnea.