Control | Intervention | P value* | |||
Intention-to-treat | As-treated | Intention-to-treat | As-treated | ||
n=221 | n=122 | n=63 | |||
API | 77.5±8.1 | 78.0±7.7 | 78.0±7.9 | 0.594 | 0.815 |
Information seeking | 88.7±8.8 | 89.7±7.7 | 90.4±7.6 | 0.850 | 0.422 |
Decision-making | 62.4±13.7 | 62.8±14.5 | 62.0±14.8 | 0.250 | 0.970 |
HADS | 7.4±5.8 | 7.3±5.9 | 7.6±6.1 | 0.954 | 0.561 |
Anxiety | 4.9±3.4 | 4.6±3.5 | 5.0±3.9 | 0.962 | 0.225 |
Depression | 2.5±2.9 | 2.6±2.9 | 2.5±2.6 | 0.887 | 0.740 |
SF-36 MCS | 75.5±16.0 | 75.4±16.9 | 75.8±15.8 | 0.346 | 0.482 |
Vitality | 65.3±18.3 | 67.2±19.3 | 67.0±17.6 | 0.066 | 0.455 |
Social functioning | 84.4±20.4 | 83.0±20.3 | 83.5±18.9 | 0.663 | 0.657 |
Role-emotional | 78.5±23.0 | 76.1±24.1 | 74.5±24.5 | 0.953 | 0.444 |
Mental health | 78.1±16.2 | 78.9±16.4 | 80.6±15.4 | 0.160 | 0.039 |
CPS (The final treatment decision should be made by) | 0.829 | 0.738 | |||
Physician | 0.5% (1) | 0.0% (0) | 0.0% (0) | ||
Physician, after considering patient opinion | 14.3% (31) | 12.2% (14) | 14.3% (9) | ||
Physician and patient together | 82.0% (178) | 80.9% (93) | 79.4% (50) | ||
Patient, after considering physician opinion | 2.8% (6) | 5.2% (6) | 4.8% (3) | ||
Patient | 0.5% (1) | 1.7% (2) | 1.6% (1) |
Data presented as ‘mean±SD’ or ‘proportion (count)’.
*All significance tests were adjusted for centre and time effects using mixed-regression models (random effect for centre and fixed effect for calendar time).
API, Autonomy Preference Index; CPS, Control Preferences Scale; HADS, Hospital Anxiety and Depression Scale; MCS, Mental Component Scale; SF-36, Short Form 36 Health Survey, .