C-indices with 95% CI for the ABC-AF-bleeding risk score in ARISTOTLE and RE-LY comparing geographic regions
| ARISTOTLE | RE-LY | |||
| C-index | 95% CI | C-index | 95% CI | |
| Major bleeding | ||||
| All | 0.677 | 0.657 to 0.698 | 0.708 | 0.684 to 0.731 |
| Asia/Pacific | 0.684 | 0.639 to 0.728 | 0.649 | 0.558 to 0.739 |
| Europe | 0.680 | 0.641 to 0.719 | 0.701 | 0.664 to 0.739 |
| Latin America | 0.674 | 0.629 to 0.719 | 0.657 | 0.561 to 0.754 |
| North America | 0.659 | 0.620 to 0.699 | 0.710 | 0.672 to 0.749 |
| Other | 0.760 | 0.698 to 0.822 | ||
ABC-AF bleeding score, Age, Biomarkers (troponin T-hs, haemoglobin, and GDF-15), Clinical history (previous bleeding); ARISTOTLE, Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation; RE-LY, Randomized Evaluation of Long-Term Anticoagulation Therapy.