Multivariate logistic regression analysis for the predictors of PPM in the S3, XT and entire cohorts
| S3 cohort | XT cohort | Entire cohort | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Age, years | 0.94 (0.9 to 0.98) | 0.003 | 0.96 (0.92 to 0.99) | 0.02 | 0.95 (0.92 to 0.98) | 0.0003 |
| BSA, m2 (per 0.1 m2 increase) | 1.76 (1.45 to 2.14) | <0.0001 | 1.43 (1.19 to 1.72) | 0.0001 | 1.58 (1.39 to 1.80) | <0.0001 |
| Body mass index, kg/m2 | 0.93 (0.86 to 1.00) | 0.06 | 0.99 (0.92 to 1.05) | 0.68 | 0.96 (0.91 to 1.01) | 0.10 |
| AVA, cm2 (per 0.1 cm2 increase) | 0.74 (0.64 to 0.85) | <0.0001 | 0.81 (0.70 to 0.92) | 0.002 | 0.77 (0.70 to 0.85) | <0.0001 |
| Area oversizing | 1.02 (1.00 to 1.04) | 0.08 | 1.03 (1.01 to 1.05) | 0.0004 | 1.02 (1.01 to 1.04) | 0.0002 |
| Balloon predilatation | 1.17 (0.75 to 1.83) | 0.49 | 1.39 (0.79 to 2.62) | 0.27 | 1.27 (0.9 to 1.81) | 0.17 |
| Balloon postdilatation | 0.30 (0.14 to 0.60) | 0.0003 | 0.51 (0.28 to 0.89) | 0.02 | 0.41 (0.25 to 0.62) | <0.0001 |
| 20 mm valve (vs 23 mm valve) | 5.67 (2.88 to 11.12) | <0.0001 | 6.27 (2.5 to 14.81) | 0.0002 | 5.26 (3.09 to 8.83) | <0.0001 |
| 20 mm valve (vs 26 mm valve) | 19.24 (8.13 to 46.86) | <0.0001 | 21.83 (7.52 to 62.10) | <0.0001 | 18.49 (9.6 to 35.85) | <0.0001 |
| 20 mm valve (vs 29 mm valve) | 51.03 (12.28 to 280.77) | <0.0001 | 47.36 (9.18 to 371.34) | <0.0001 | 43.07 (14.66 to 149.18) | <0.0001 |
| 23 mm valve (vs 26 mm valve) | 3.39 (1.91 to 6.24) | <0.0001 | 3.48 (2.01 to 6.26) | <0.0001 | 3.52 (2.36 to 5.34) | <0.0001 |
| 23 mm valve (vs 29 mm valve) | 8.99 (2.64 to 42.85) | 0.0002 | 7.56 (2.01 to 49.78) | 0.001 | 8.20 (3.27 to 25.28) | <0.0001 |
| 26 mm valve (vs 29 mm valve) | 2.65 (0.79 to 12.41) | 0.12 | 2.17 (0.59 to 14.03) | 0.27 | 2.33 (0.94 to 7.08) | 0.07 |
| SAPIEN3 (vs SAPIENXT) | – | – | – | – | 1.92 (1.35 to 2.74) | 0.0003 |
AVA, aortic valve area; BSA, body surface area; PPM, prosthesis–patient mismatch; S3, SAPIEN 3; XT, SAPIEN XT.