14 October 2019–30 December 2019 | 13 January 2020–27 March 2020 | 27 March 2020–22 May 2020 | 14 October 2019–27 March 2020 | |
Total | 14 (7.8%) | 28 (15.4%) | 31 (20.4%) | 73 |
Female | 5 (35.7%) | 14 (50%) | 12 (38.7%) | 31 (42.5%) |
Age | 61.1 (57.8–67.4) | 50.5 (44.8–56.5) | 54 (50–60.5) | 55 (49–60) |
Length of stay (days) | 4.2 (2.16–5.5) | 1.98 (1.4–2.4) | 2.5 (1.9–4.5) | 2.2 (1.7–4.3) |
Family history | 5 (36%) | 8 (28.6%) | 10 (32.3%) | 23 (31.5%) |
Hypertension | 6 (42.9%) | 4 (14.3%) | 10 (32.3%) | 20 (27.4%) |
Diabetes mellitus | 2 (14.3%) | 1 (3.6%) | 0 (0%) | 3 (4.1%) |
Smoker | Current=4 (28.6%) Ex=6 (42.8%) Never=4 (28.6%) | Current=9 (32.1%) Ex=7 (25%) Never=12 (42.9%) | Current=9 (29%) Ex=11 (35.5%) Never=11 (35.5%) | Current=22 (30.1%) Ex=24 (32.9%) Never=27 (37%) |
Dyslipidaemia | 5 (35.7%) | 12 (42.9%) | 10 (32.3%) | 27 (37%) |
History of cardiovascular/cerebrovascular disease | 0 (0%) | 3 (10.7%) | 0 (0%) | 3 (4.1%) |
Weight (kg) | 74 (64–80.8)* | 72 (65.8–78.8)* | 80.2 (74.5–88.2)* | 76 (69–83.5)* |
New ECG ischaemia | 1 (7.1%) | 4 (14.3%) | 2 (6.4%) | 7 (9.6%) |
Troponin-T (ng/L) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
Exercise stress test | 6 (42.9%) | 7 (25%) | 0 (0%) | 13 (17.8%) |
Time to CTCA (hours) | 23 (6.8–45.3) | 20.16 (16.8–32.3) | 30.1 (0.4–92.5) | 22 (8.2–43.5) |
Calcium score | 68.45 (1.6–103.9)† | 0 (0–6) | 0 (0–25)† | 0 (0–31)† |
% CTCA with an abnormal finding | 57 | 35.7 | 54.8 | 47.9 |
Beta-blocker used for rate control | 7 nebivolol (50%) 3 metoprolol (IV) (21.4%) 2 metopolol (PO) (14.3%) 1 bisoprolol (7.15%) 1 none needed (7.15%) | 21 nebivolol (75%) 4 metoprolol (PO) (14.3%) 2 metoprolol (IV) (7.1%) 1 propranolol (3.6%) | 17 nebivolol ( 9 metoprolol (IV) 3 none needed 1 bisoprolol 1 unable to control | 45 nebivolol (61.6%) 14 metoprolol (IV) (19.2%) 6 metoprolol (PO) (8.2%) 4 none needed (5.5%) 2 bisoprolol (2.7%) 1 propranolol (1.3%) 1 unable to control (1.3%) |
Invasive coronary angiography | 5 (35.7%) | 5 (17.8%) | 7 (22.6%) | 17 (23.3%) |
Revascularisation performed | 3 (21.4%) | 3 (10.7%) | 2 (6.5%) | 8 (10.9) |
Alive at 1 month | 14 | 28 | 31 | 73 (100%) |
Myocardial infarction at 1 month | 0 | 0 | 0 | 0 |
*Weight: not available=3 in cohort 1, 4 in cohort 2, 5 in cohort 3
†Calcium score: not available=4 in cohort 1, 4 in cohort 3.
CTCA, CT coronary angiography.