Baseline characteristics of proband subjects with HCM
| Sarcomere negative N=59 | Sarcomere positive N=68 | P value | Adjusted p value | |
| Age at diagnosis (years) | 51.0 (39.5,59.0) 48±14.5 | 32.5 (16.8,46.3) 32±16.8 | <0.0001 | |
| Male (n) | 38 (64%) | 35 (51%) | 0.15 | |
| Systolic BP (mm Hg) | 123 (112,137) 126.5±18.9 | 120 (107,128) 119±16.3 | 0.0253 | 0.398 |
| Diastolic BP (mm Hg) | 74 (67,81) 74.3±9.5 | 70 (62,78) 69.5±10.1 | 0.0242 | 0.196 |
| Mean arterial pressure (mm Hg) | 91.3 (83.3,99.2) 91.7±11.4 | 86.7 (78.3,93.3) 85.9±10.9 | 0.0163 | 0.232 |
| BSA (m2) | 2.14 (1.95,2.22) 2.09±0.25 | 1.91 (1.73,2.11) 1.90±0.33 | 0.0008 | 0.003 |
| BMI (kg/m2) | 31.1 (27.7,34.9) 31.7±5 | 27.7 (23.3,33.7) 28.2±6.9 | 0.0026 | 0.037 |
All values expressed as median (25% percentile, 75% percentile) and mean±SD.
BMI, body mass index; BP, blood pressure; BSA, body surface area; HCM, hypertrophic cardiomyopathy.