Table 2

Myocardial hypertrophy and LVOT obstruction

Sarcomere
negative
N=59
Sarcomere
positive
N=68
P value
LVWTmax (mm)*20 (18,22)
20.3±4.1
21 (18,27)
22.6±6.5
0.0686
Ratio LVWTmax:LVWTmin*1.8 (1.57,2.1)
1.84±0.4
2.1 (1.66,3.0)
2.48±1.1
0.0011
LVWTmax/BSA (mm/mm2)*9.6 (8.1,10.7)
9.9±2.3
10.9 (8.9,13.8)
12.3±4.8
0.0006
LVOT obstruction (%)†32 (54)24 (35)0.0483
LVOT gradient (mm Hg)*105 (43,141)
98.5±56.3
71 (43,91)
75±51.3
0.1050
  • *Values expressed as median (25% percentile, 75% percentile) and mean±SD.

  • †LVOT obstruction defined as LVOT gradient >30 mm Hg.

  • BSA, body surface area; LVOT, left ventricular outflow tract; LVWTmax, maximum left ventricular wall thickness; LVWTmin, minimum left ventricular wall thickness.