Invasive management (coronary angiography±PCI) in trial and registry patients at baseline (index admission) and follow-up (≥18 months)
| Patients with procedures at baseline and follow-up | Trial N=46 (%) | Registry N=40 (%) | P value |
| Patients with one procedure | 37 (80.4) | 32 (80.0) | 0.084 |
| Patients with two procedures | 8 (17.4) | 4 (10.0) | |
| Patients with three procedures | 0 (0) | 4 (10.0) | |
| Patients with four procedures | 1 (2.2) | 0 (0) | |
| Patients with PCI at baseline | 10 (21.7) | 13 (32.5) | 0.331 |
| Patients with PCI at baseline and follow-up | 21 (45.7) | 18 (45.0) | 1.000 |
| Days from enrolment to patient’s first procedure | 22.5 (6.5-64.75) | 1.5 (0-7.25) | <0.001 |
| <30 days | 25 (54.3) | 36 (90.0) | <0.001 |
| 30–59 days | 9 (19.6) | 0 (0) | |
| ≥60 days | 12 (26.1) | 4 (10.0) | |
| Procedures at baseline |
Trial
n=31 |
Registry
n=36 | P-value |
| BCIS Jeopardy Score (pre-PCI) at baseline* | 4.3±3.7 | 5.4±3.1 | 0.189 |
| PCI at baseline | 10 (32.3) | 13 (36.1) | 0.800 |
| BCIS Jeopardy Score (post-PCI) at baseline | 2.4±2.5 | 4.0±3.4 | 0.220 |
| Procedures at baseline and follow-up |
Trial
n=57 |
Registry
n=52 | P-value |
| Urgent in-patient procedure | 27 (47.4) | 39 (75.0) | 0.004 |
| Outpatient procedure | 30 (52.6) | 13 (25.0) | |
| Hospitalisation† | 28 (49.1) | 41 (78.8) | 0.002 |
| Complications related to angiogram‡ | 1 (1.8) | 6 (11.5) | 0.052 |
| Culprit vessel uncertain | 27 (47.4) | 21 (40.4) | 0.563 |
| Culprit vessel identified | 30 (52.6) | 31 (59.6) | |
| Graft only | 17 (56.7) | 15 (48.4) | 0.611 |
| Native artery only | 12 (40.0) | 15 (48.4) | 0.609 |
| Both graft and native artery | 1 (3.3) | 1 (3.2) | 1.000 |
| Multiple culprit lesions | 3 (10.0) | 2 (6.5) | 0.671 |
| PCI at baseline and follow-up | 24 (42.1) | 25 (48.1) | 0.567 |
| Thrombus aspiration | 1 (4.2) | 0 (0) | 0.490 |
| Rotational atherectomy | 4 (16.7) | 0 (0) | 0.050 |
| Intravascular ultrasound | 2 (8.3) | 3 (12.0) | 1.000 |
| Distal protection device | 3 (12.5) | 2 (8.0) | 0.667 |
Mean±SD and median (IQR) for non-normally distributed data.
*BCIS Jeopardy score not available in one registry patient because of poor-quality angiogram and limited data for right coronary artery (only still frame and not a run).
†Admission to hospital including at least one overnight stay.
‡Complications in trial (N=1) was worsening renal function after angiography; complications in registry (N=6) were side branch abrupt closure, main branch distal embolisation into filter, no reflow, dissection post-angioplasty (+haematoma > 5 cm in same patient), pulmonary oedema on angiography table, side branch new/worsened thrombus.
BCIS, British Cardiovascular Intervention Society; PCI, percutaneous coronary intervention.