Table 1

Clinical characteristics

	All	Event (+)	Event (-)	P value
Number	140	25	115	–
Age	61±12	62±10	60±12	0.54
Male, %	14 (10)	1 (4)	13 (11)	0.11
Body mass index	22±3	22±3	22±3	0.88
WHO Class I/II/III/IV	27/82/31/0	5/16/4/0	22/66/27/0	0.54
History
Disease duration, months	1.7	1.5	1.7	0.75
Medication
Antihypertensive drugs, %	2 (1)	0 (0)	2 (2)	0.16
Diuretic, %	3 (2)	1 (4)	2 (2)	0.59
Anticoagulants, %	0 (0)	0 (0)	0 (0)	–
Respiratory function
%EFV₁, %	80±4	82±6	79±4	0.82
%FVC, %	109±13	113±15	107±12	0.34
%DLCO	80±13	81±14	79±11	0.53
Baseline haemodynamics
HR, bpm	68±12	68±10	67±12	0.67
Systolic BP, mm Hg	123±20	122±22	123±19	0.93
Diastolic BP, mm Hg	68±10	68±10	69±10	0.68
SpO₂, %	98±1	97±2	98±1	0.53
Post-6-minute walk haemodynamics
HR, bpm	90±17	92±18	89±16	0.54
Systolic BP, mm Hg	128±25	129±22	128±25	0.79
Diastolic BP, mm Hg	66±15	70±19	65±14	0.22
SpO₂, %	96±3	96±2	96±3	0.80
6MW distance, m	432±89	451±94	428±87	0.26

Data are presented as number of patients (percentage) and mean±SD.
BP, blood pressure; %DLCO, diffusing capacity for carbon monoxide; %FEV1, percent forced expiratory volume in 1 s; %FVC, percent forced vital capacity; HR, heart rate; MCTD, mixed connective tissue disease; SpO₂, percutaneous oxygen saturation; SSc, systemic sclerosis.