Haemodynamic parameters
| All | Event (+) | Event (-) | P value | |
| Rest echocardiographic variables | ||||
| LVEDVi, mL/m2 | 49±11 | 49±14 | 49±10 | 0.87 |
| LVESVi, mL/m2 | 17±4 | 17±6 | 17±4 | 0.59 |
| LVEF, % | 65±4 | 66±3 | 65±4 | 0.15 |
| LVMi, g/m2 | 75±17 | 72±19 | 76±16 | 0.31 |
| LAVi, mL/m2 | 29±9 | 29±12 | 28±9 | 0.79 |
| e’, cm/s | 10±3 | 11±3 | 10±3 | 0.27 |
| E/e' | 7±3 | 8±4 | 7±3 | 0.09 |
| RVEDA, cm2 | 14±3 | 13±3 | 14±3 | 0.10 |
| RVESA, cm2 | 8±2 | 8±2 | 8±2 | 0.78 |
| RVFAC, % | 44±10 | 41±12 | 45±10 | 0.14 |
| TAPSE, mm | 22±4 | 21±4 | 22±4 | 0.50 |
| GLS, % | 19±3 | 18±2 | 19±3 | 0.19 |
| RVLS, % | 25±6 | 25±7 | 25±6 | 0.87 |
| Exercise haemodynamics | ||||
| Mean PAP, mm Hg | 17±3 | 18±3 | 17±3 | 0.29 |
| Mean PAWP, | 11±4 | 12±4 | 11±4 | 0.09 |
| CO, L/min | 3.8±1.2 | 4.1±1.7 | 3.8±1.1 | 0.41 |
| PVR, wood unit | 1.9±1.1 | 1.9±0.8 | 1.9±1.2 | 0.57 |
| Exercise mean PAP, mm Hg | 23±5 | 25±4 | 23±5 | 0.05 |
| Exercise mean PAWP, mm Hg | 13±4 | 14±5 | 12±4 | 0.04 |
| Exercise CO, L/min | 6.1±2.1 | 5.6±2.1 | 6.2±2.1 | 0.19 |
| Exercise PVR, wood unit | 1.9±1.0 | 2.2±1.1 | 1.9±0.9 | 0.17 |
| ΔmPAP/ΔCO, mm Hg/L/min | 4.1±2.5 | 8.9±3.8 | 3.0±1.7 | 0.008 |
| ΔmPAWP/ΔCO, mm Hg/L/min | 1.1±0.6 | 2.2±0.9 | 0.9±0.5 | 0.004 |
| Δe’, cm/s | 0.9±3.1 | 0.5±3.6 | 1.0±3.1 | 0.63 |
Data are presented as number of patients (percentage) and mean±SD.
CO, cardiac output; e’, early diastolic mitral annular motion; E, early diastolic transmitral flow velocity; LAVi, left atrial volume index; LVEDVi, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVESVi, left ventricular end-systolic volume index; LVMi, left ventricular mass index; mPAP, mean pulmonary artery pressure; mPAWP, mean pulmonary artery wedge pressure; PVR, pulmonary vascular resistance; RVEA, right ventricular end-diastolic area; RVESA, right ventricular end-systolic area; RVFAC, right ventricular functional area change; TAPSE, tricuspid annular plane systolic excursion.