Table 4

Multivariate associations of outcomes

	Multivariate model
	HR	95% CI	P value
ΔmPAP/ΔCO, mm Hg/L/min	1.18	1.05 to 1.32	0.006
ΔmPAWP/ΔCO, mm Hg/L/min	2.12	1.46 to 3.06	<0.001
ΔmPAP/ΔCO×ΔmPAWP/ΔCO	0.96	0.93 to 0.99	0.016

CO, cardiac output; mPAP, mean pulmonary artery pressure; mPAWP, mean pulmonary artery wedge pressure.;