Echocardiographic variables
| Ventricular functional MR N=288 | Atrial functional MR N=90 | P value | |
| LV end-diastolic dimension, mm | 64 (58–72) | 52 (48–57) | <0.001 |
| LV end-systolic dimension, mm | 55 (48–64) | 34 (31–37) | <0.001 |
| LV ejection fraction, % | 28 (19–35) | 55 (50–60) | <0.001 |
| Interventricular septal thickness, mm | 8.1±2.2 | 8.9±1.6 | 0.003 |
| Posterior wall thickness, mm | 8.3±2.0 | 9.0±1.5 | <0.001 |
| LA diameter, mm | 48 (43–54) | 52 (47–61) | <0.001 |
| LA volume index, mL/m2 | 73 (57–91) | 99 (73–137) | <0.001 |
| Tricuspid regurgitation, n (%) | 28 (10) | 35 (39) | <0.001 |
| Tricuspid regurgitation pressure gradient, mm Hg | 33 (23–43) | 30 (25–38) | 0.18 |
| Quantitative MR severity | |||
| Volumetric method | |||
| Regurgitant volume, mL | 47 (37–59) | 45 (41–60) | 0.61 |
| Regurgitant fraction, % | 50 (45–56) | 46 (38–55) | 0.08 |
| PISA method | |||
| Regurgitant volume, mL | 48 (40–61) | 49 (39–65) | 0.77 |
| Effective regurgitant orifice area, cm2 | 0.32 (0.26–0.40) | 0.31 (0.24–0.45) | 0.95 |
Numeric values are expressed as mean±SD or median (IQR).
LA, left atrium; LV, left ventricle; MR, mitral regurgitation; PISA, proximal isovelocity surface area.