Univariate Cox regression for predictors of shorter time to VT/VF postdiagnosis
Feature | HR | 95% CI | P value |
Female | 0.219 | (0.030 to 1.59) | 0.133 |
Age of initial presentation | 1.00 | (0.983 to 1.02) | 0.874 |
Initial syncope | 2.24 | (1.11 to 4.53) | 0.025 |
Initial VT/VF | 11.3 | (6.32 to 20.3) | <0.0001 |
Initial type 1 BrP | 0.981 | (0.551 to 1.75) | 0.949 |
Evolution | 0.562 | (0.296 to 1.07) | 0.078 |
Fever | 0.435 | (0.135 to 1.40) | 0.163 |
Family History of BrS | 0.536 | (0.074 to 3.90) | 0.538 |
Family History of VF/SCD | 0.845 | (0.262 to 2.72) | 0.778 |
Other arrhythmia | 3.02 | (1.67 to 5.45) | <0.0001 |
EPS positive | 3.29 | (0.954 to 11.3) | 0.059 |
Abnormal Holter | 2.85 | (0.835 to 9.74) | 0.095 |
Genetic positive | 0.504 | (0.135 to 1.88) | 0.308 |
Average | |||
Heart rate | 1.01 | (0.992 to 1.02) | 0.324 |
PWD | 1.00 | (0.981 to 1.03) | 0.732 |
PR interval | 0.999 | (0.987 to 1.01) | 0.858 |
QRS duration | 1.02 | (1.00 to 1.03) | 0.027 |
QT interval | 1.00 | (0.995 to 1.01) | 0.332 |
QTc Interval | 1.01 | (1.00 to 1.02) | 0.013 |
P axis | 1.01 | (0.982 to 1.03) | 0.616 |
QRS Axis | 0.997 | (0.990 to 1.00) | 0.307 |
T Axis | 1.00 | (0.988 to 1.01) | 0.877 |
V5 R wave amplitude | 0.895 | (0.459 to 1.75) | 0.745 |
V1 S wave amplitude | 0.519 | (0.157 to 1.71) | 0.282 |
SD | |||
Heart rate | 1.01 | (0.966 to 1.05) | 0.780 |
PWD | 1.04 | (1.00 to 1.09) | 0.033 |
PR interval | 1.01 | (0.984 to 1.03) | 0.510 |
QRS duration | 1.02 | (0.988 to 1.05) | 0.247 |
P axis | 1.01 | (0.982 to 1.03) | 0.616 |
QRS axis | 1.01 | (1.00 to 1.02) | 0.048 |
T axis | 1.00 | (0.982 to 1.02) | 0.730 |
V5 R wave amplitude | 1.37 | (0.192 to 9.79) | 0.752 |
V1 S wave amplitude | 2.29 | (0.053 to 99.7) | 0.666 |
Baseline | |||
Heart rate | 1.01 | (0.990 to 1.02) | 0.489 |
PWD | 1.01 | (0.982 to 1.03) | 0.668 |
PR interval | 1.00 | (0.989 to 1.01) | 0.879 |
QRS duration | 1.00 | (0.992 to 1.01) | 0.580 |
QT interval | 1.00 | (0.997 to 1.01) | 0.255 |
QTc interval | 1.01 | (1.00 to 1.02) | 0.022 |
P axis | 0.998 | (0.985 to 1.01) | 0.788 |
QRS axis | 0.999 | (0.993 to 1.00) | 0.713 |
T axis | 1.00 | (0.989 to 1.01) | 0.989 |
V5 R wave amplitude | 0.632 | (0.296 to 1.35) | 0.236 |
V1 S wave amplitude | 0.419 | (0.105 to 1.67) | 0.219 |
P-values less than 0.05 are shown in bold text.
BrP, Brugada pattern; BrS, Brugada syndrome; EPS, electrophysiological study; PWD, P-wave duration; QTc, corrected QT interval; SCD, sudden cardiac death; VF, ventricular fibrillation; VT, ventricular tachycardia.