Study | Design | Imaging tool | Population | Parameter | Mean value | Cut-off value to predict outcome |
Magne et al6 | Retrospective observational study | 2D Echocardiography | Non-FMR (n=20) | Tenting area (cm2) | 0.95±0.2 | 2.5 cm2 |
Non-persistent MR (n=40) | 1.72±0.4 | |||||
Persistent MR (n=11) | 2.70±0.9 | |||||
Karaca et al7 | Prospective observational study | 2D Echocardiography | Non-FMR (n=49) | Tenting area (cm2) | No values | 3.4 cm2 |
Severe FMR (n=41) | No values | |||||
Dwivedi et al13 | Population-based prospective study | 2D Echocardiography | Healthy subjects (n=480) | Tenting area (cm2) | Male: 2.02±0.68 Female: 1.64±0.47 | |
Indexed tenting area (cm2/m2) | Male: 1.02±0.34 Female: 0.93±0.27 | |||||
Nishino et al17 | Prospective observational study | 2D Echocardiography | Non-FMR (n=14) | Indexed tenting area (cm2/m2) | 0.42 (0.37–0.44) | |
Acute FMR (n=44) | 1.02 (0.82–1.15) | |||||
Chronic FMR (n=36) | 1.56 (1.28–1.77) | |||||
Nappi et al8 | Post hoc analysis of prior published randomised trial | 2D Echocardiography | Severe FMR (n=48) | Tenting area (cm2) | 3.0±0.3 | 3.1 cm2 |
Von Stumm et al5 | Retrospective observational study | 2D Echocardiography | Severe FMR (n=240) | Tenting area (cm2) | 2.8±0.8 | 2.4 cm2 |
2D, two-dimensional; MR, mitral regurgitation.