Table 1

Clinical characteristics

All (n=873)Male (n=398)Female (n=475)P value
Age, mean (SD), years80.0 (7.2)78.9 (7.5)80.8 (6.8)<0.001
Weight, mean (SD), kg56.7 (12.3)62.2 (11.5)52.3 (11.0)<0.001
Height, mean (SD), cm155.7 (9.8)163.3 (7.1)149.4 (7.0)<0.001
BSA, mean (SD)1.56 (0.20)1.67 (0.17)1.47 (0.17)<0.001
BMI, mean (SD)23.4 (4.1)23.3 (3.8)23.4 (4.4)0.74
Logistic EuroSCORE (SD)18.5 (14.4)17.5 (13.6)19.3 (14.9)0.07
DM, n (%)274 (31.4)125 (31.4)149 (31.4)0.97
HPT, n (%)663 (75.9)305 (76.6)358 (75.4)0.74
Lipids, n (%)475 (54.4)218 (54.8)257 (54.1)0.67
Smoker, n (%)150 (17.2)129 (32.4)21 (4.4)<0.001
IHD449 (51.4)228 (57.3)221 (46.5)0.002
Prior PCI, n (%)301 (34.5)157 (39.4)144 (30.3)0.005
Prior CABG, n (%)111 (12.7)68 (17.1)43 (9.1)<0.001
Carotid artery stenosis >50%, n (%)72 (8.2)33 (8.3)39 (8.2)0.86
Peripheral vascular disease, n (%)158 (18.1)78 (19.6)80 (16.8)0.24
Prior valve replacement, n (%)25 (2.9)3 (0.8)22 (4.6)<0.001
NYHA class, mean2.8 (0.7)2.8 (0.7)2.8 (0.7)0.25
NYHA class III or IV, n (%)580 (66.4)259 (65.1)321 (67.6)0.35
EF, % (SD)58 (13)55 (14)59 (13)<0.001
AVA, mean (SD), cm20.66 (0.19)0.70 (0.18)0.63 (0.19)<0.001
Indexed AVA, mean (SD), cm2/m20.43 (0.12)0.42 (0.11)0.43 (0.13)0.07
MPG, mean (SD), mm Hg50.9 (18.8)51.0 (18.5)50.8 (19.0)0.87
Annulus, mean (SD), mm22.3 (3.1)23.8 (3.6)21.0 (1.9)<0.001
AR >grade 2, n (%)152 (17.4)66 (16.6)86 (18.1)0.29
MR >grade 2, n (%)116 (13.3)58 (14.6)58 (12.2)0.69
Renal disease, n (%)53 (6.1)26 (6.5)27 (5.7)0.74
Lung disease, n (%)37 (4.2)25 (6.3)12 (2.5)0.02
Calcified aorta, n (%)44 (5.0)18 (4.5)26 (5.5)0.25
Pulmonary hypertension, n (%)9 (1.0)5 (1.3)4 (0.8)0.69
Previous CVA, n (%)6 (0.7)2 (0.5)4 (0.8)0.68
Minimal femoral diameter, mean (SD), mm*7 (1.7)7.3 (1.8)6.3 (1.5)<0.001
  • *Data taken from Chiam et al19 in a cohort of Asian patients with similar physical stature.

  • AR, aortic regurgitation; AVA, aortic valve area ; BMI, body mass index; BSA, body surface area; CABG, coronary artery bypass grafting; CVA, cerebrovascular accident; DM, diabetes mellitus; EF, ejection fraction; HPT, hypertension; IHD, ischaemic heart disease; MPG, mean pressure gradient; MR, mitral regurgitation; NYHA, New York Heart Association; PCI, percutaneous coronary intervention.