Table 3

Comparisons of female patients corrected for TOF without and with history of VA, and markers for VA adjusted for age

TOF without VA n=63 (79%)TOF with VA n=17 (21%)P valueOR
(95% CI)
P value
Age, years36±940±90.08
Height, cm165±7166±90.81
Weight, kg68±1363±100.25
History of pregnancy, n (%)39 (61)16 (94)0.0213 (1.5 to 113.2)0.02*
HR, bpm68±1162±80.13
SBP, mm Hg115±11115±130.98
DBP, mm Hg68±971±120.44
QTc duration, ms458±31450±270.52
Exercise capacity, W125±25140±260.13
NYHA class1 (1–3)1 (1–2)0.66
NT-proBNP, ng/L139 (30–465)211 (127–836)0.0071.4 (1.1 to 1.7)0.017*
QRS duration, ms135 (82–174)133 (86–152)0.45
RV EDV, mL21.1±4.122.7±3.60.16
RV ESV, mL11.1±2.611.8±2.50.33
RV FAC, %47±747±80.93
RV D3, cm7.3±0.77.4±0.70.54
PV vel, m/s1.9±0.61.8±0.40.39
Mod-sev PV reg12 (19%)2 (12%)0.47
LV MD, ms43±1348±160.24
LV GLS, %−19.2±3.1−17.5±3.60.10
RV MD, ms39±1450±80.009
0.016
2.1 (1.3 to 7.5)
5.7 (3.5 to 9.2)
0.01*
0.03†
RV GLS, %−19.7±4.1−18.3±4.10.28
RVOT, cm2.9±0.43.1±0.60.31
LVEF, %56±954±80.39
  • Data are presented as mean±SD or median with range, as appropriate; p value from Student’s t-test or Mann-Whitney U test as appropriate, and multivariable logistic regression.

  • *Adjusted for age at VA.

  • †Adjusted for age at echocardiography.

  • DBP, diastolic blood pressure; EDV, end-diastolic volume; ESS, end-systolic strain; ESV, end-systolic volume; GLS, global longitudinal strain; HR, heart rate; LV, left ventricular; LVEF, left ventricular ejection fraction; MD, mechanical dispersion; NT-proBNP, N-terminal pro-brain natriuretic peptide; NYHA, New York Heart Association classification; PV, pulmonary valve; RV, right ventricular; RV D3, right ventricular longitudinal diameter; RV FAC, right ventricular fractional area change; RVOT, right ventricular outflow tract; SBP, systolic blood pressure; TOF, tetralogy of Fallot; VA, ventricular arrhythmia.