Clinical characteristics before discharge in patients with low and high Ed/Ea
| Ed/Ea | P value (low vs high) | ||
| ≤0.144 (n=376) | >0.144 (n=176) | ||
| Age, years | 80±9 | 83±9 | 0.002 |
| Male sex, n (%) | 195 (52) | 60 (34) | <0.001 |
| Systolic blood pressure, mm Hg | 122±17 | 116±16 | <0.001 |
| Diastolic blood pressure, mm Hg | 67±11 | 63±11 | <0.001 |
| Heart rate, bpm | 72±13 | 71±14 | 0.649 |
| Atrial fibrillation, n (%) | 142 (38) | 58 (33) | 0.273 |
| Chronic obstructive pulmonary disease, n (%) | 26 (7) | 9 (5) | 0.534 |
| Coronary artery disease, n (%) | 72 (19) | 46 (26) | 0.062 |
| Diabetes mellitus, n (%) | 130 (35) | 64 (36) | 0.681 |
| Dyslipidaemia, n (%) | 156 (41) | 78 (44) | 0.531 |
| Hypertension, n (%) | 320 (85) | 157 (89) | 0.190 |
| Laboratory data | |||
| Albumin, g/dL | 3.4±0.5 | 3.4±0.5 | 0.607 |
| eGFR, mL/min/1.73 m2 | 44.3±18.9 | 39.2±18.7 | 0.003 |
| Haemoglobin, g/dL | 11.5±2.1 | 11.1±1.9 | 0.061 |
| N-terminal pro-brain natriuretic peptide, pg/mL | 2202±4406 | 3669±8963 | 0.014 |
| Echocardiographic data | |||
| LAD, mm | 43±8 | 46±8 | <0.001 |
| LAVI, mL/m2 | 52±24 | 60±26 | <0.001 |
| LVEDVI, mL/m2 | 54±21 | 54±20 | 0.989 |
| LVESVI, mL/m2 | 22±11 | 21±10 | 0.405 |
| SVI, mL/m2 | 32±12 | 33±13 | 0.515 |
| SV/LAV | 0.74±0.41 | 0.65±0.35 | 0.010 |
| LVEF, % | 60±7 | 61±8 | 0.311 |
| TAPSE, mm | 17.7±4.4 | 17.4±4.6 | 0.481 |
| E/e' | 10.9±2.9 | 19.6±4.8 | <0.001 |
| Medications | |||
| Beta-blockers, n (%) | 207 (55) | 96 (55) | 0.911 |
| Calcium channel blockers, n (%) | 197 (52) | 93 (53) | 0.921 |
| Diuretics, n (%) | 309 (82) | 152 (86) | 0.217 |
| RAAS inhibitors, n (%) | 272 (72) | 136 (77) | 0.218 |
| Statins, n (%) | 122 (32) | 65 (37) | 0.299 |
Values are presented as means±SD or numbers (%).
Ea, arterial elastance; Ed, diastolic elastance; eGFR, estimated glomerular filtration rate; LAD, left atrial diameter; LAV, left atrial volume; LAVI, left atrial volume index; LVEDVI, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVESVI, left ventricular end-systolic volume index; RAAS, renin-angiotensin-aldosterone system; SV, stroke volume; SVI, stroke volume index; TAPSE, tricuspid annular plane systolic excursion.