Baseline characteristics of the population
| Total (N=442) | Placebo (N=222) | Metoprolol (N=220) | P value | |
| Patient demographics | ||||
| Age (years) | 62.5±11.6 | 62.9±11.8 | 62±11.4 | 0.41 |
| Male sex | 331/442 (74.89%) | 162/222 (72.97%) | 169/220 (76.82%) | 0.38 |
| Prior MI | 17/440 (3.86%) | 8/221 (3.62%) | 9/219 (4.11%) | 0.81 |
| Prior PCI | 29/441 (6.58%) | 12/221 (5.43%) | 17/220 (7.73%) | 0.34 |
| Prior CVA | 11/4441 (2.48%) | 4/221 (1.81%) | 7/220 (3.18%) | 0.38 |
| Renal failure | 8/436 (1.83%) | 5/218 (2.29%) | 3/218 (1.38%) | 0.72 |
| Peripheral VD | 8/441 (1.81%) | 5/221 (2.26%) | 3/220 (1.36%) | 0.72 |
| Risk factors | ||||
| Smoking | 175/409 (42.79%) | 90/202 (44.55%) | 85/207 (41.06%) | 0.48 |
| Family history | 163/391 (41.69%) | 82/192 (42.71%) | 81/199 (40.07%) | 0.75 |
| Hypertension | 170/440 (38.64%) | 84/220 (38.18%) | 86/220 (39.09%) | 0.92 |
| Hypercholesterolaemia | 108/433 (24.94%) | 52/217 (23.96%) | 56/216 (25.93%) | 0.65 |
| Diabetes mellitus | 67/442 (15.16%) | 38/222 (17.12%) | 29/220 (13.18%) | 0.28 |
| Infarct location | 0.21 | |||
| Anterior | 173/384 (45.05%) | 95/194 (48.97%) | 78/190 (41.05%) | |
| Inferior | 174/384 (45.31%) | 77/194 (39.69%) | 97/190 (51.05%) | |
| Lateral | 27/384 (7.03%) | 16/194 (8.25%) | 11/190 (5.79%) | |
| Posterior | 6/384 (1.56%) | 4/194 (2.06%) | 2/190 (1.05%) | |
| Unknown | 4/384 (1.04%) | 2/194 (1.03%) | 2/190 (1.05%) | |
| Heart frequency | 78.2 (18.1) | 77.8 (18.6) | 78.6 (17.7) | 0.67 |
| Rhythm | 0.25 | |||
| SR | 386/409 (94.38%) | 193/203 (95.07%) | 193/206 (93.69%) | |
| AF | 19/409 (4.65%) | 8/203 (3.94%) | 11/206 (5.34%) | |
| Other | 2/409 (0.49%) | 0/203 | 2/206 (0.97%) | |
| ST deviation >3 mm | 357/369 (96.75%) | 180/184 (97.83%) | 177/185 (95.68%) | 0.38 |
| Categories of ST deviation | 0.42 | |||
| Normalised ST segment | 8/369 (2.17%) | 3/184 (1.63%) | 5/185 (2.7%) | |
| 1–3 mm deviation | 4/369 (1.08%) | 1/184 (0.54%) | 3/185 (1.62%) | |
| 4–6 mm deviation | 30/369 (8.13%) | 12/184 (6.52%) | 18/185 (9.73%) | |
| >6 mm deviation | 327/369 (88.62%) | 168/184 (91.3%) | 159/185 (85.95%) |
Data are n/N (%) or mean (±SD).
.AF, atrial fibrillation; CVA, cerebral vascular accident; MI, myocardial infarction; PCI, percutaneous coronary intervention; SR, sinus rhythm; VD, vascular disease.;