In-hospital data
| All patients (n=1252) | CAD (n=124) | No CAD (n=1128) | Difference (95% CI) | |
| Clinical presentation | ||||
| Systolic blood pressure, mm Hg | 121±19 | 121±21 | 121±19 | −0.7 (−4.3 to 2.8) |
| Heart rate, bpm | 90.4±15.9 | 84.0±14.4 | 91.1±19.1 | −7.1 (−10.0 to −4.2) |
| PaO2, mm Hg | 63.6±15.7 | 59.9±15.7 | 64.0±15.7 | −4.2 (−7.1 to −1.3) |
| Chest X-ray | 1003 (80.1%) | 97 (78.2%) | 906 (80.3%) | −2.1 (−9.5 to 5.3) |
| Bilateral lung infiltrate | 964 (96.4%) | 94 (96.9%) | 870 (96.3%) | 0.6 (−3.3 to 4.5) |
| Chest CT scan | 980 (78.3%) | 92 (74.2%) | 888 (78.7%) | −4.5 (−12.2 to 3.1) |
| Bilateral lung infiltrate | 954 (97.3%) | 87 (94.6%) | 867 (97.6%) | −3.1 (−6.5 to 0.4) |
| Pericardial effusion | 37 (3.8%) | 1 (1.1%) | 36 (4.1%) | −3.0 (−7.1 to 1.1) |
| Pneumomediastinum | 6 (0.6%) | 0 (0.0%) | 6 (0.7%) | −0.7 (−2.4 to 1.0) |
| Clinical outcomes | ||||
| ARDS | 615 (49.2%) | 91 (73.4%) | 524 (46.5%) | 26.9 (17.7 to 36.1) |
| Time from hospitalisation to ARDS, days | 1.6±3.8 | 2.5±5.7 | 1.5±3.4 | 1 (0.1 to 1.8) |
| Time from symptoms onset to ARDS, days | 7.4±5.5 | 8.0±6.6 | 7.3±5.3 | 0.7 (−0.5 to 1.9) |
| CPAP | 480 (38.3%) | 71 (57.3%) | 409 (36.3%) | 21.0 (12.0 to 30.0) |
| Time from hospitalisation to CPAP, days | 2.8±11.3 | 3.2±6.2 | 2.7±11.9 | 0.5 (−2.4 to 3.3) |
| Time from symptoms onset to CPAP, days | 8.7±11.8 | 8.7±7.0 | 8.7±12.4 | 0 (−2.9 to 3.0) |
| Intubation | 120 (9.6%) | 12 (9.7%) | 108 (9.6%) | 0.1 (−5.4 to 5.6) |
| Time from hospitalisation to intubation, days | 3.5±5.5 | 8.2±9.2 | 3.0±4.7 | 5.2 (2.1 to 8.4) |
| Time from symptoms onset to intubation, days | 9.3±6.5 | 16.4±10.1 | 8.5±5.6 | 7.8 (4.2 to 11.5) |
| Death | 252 (20.1%) | 55 (44.4%) | 197 (17.5%) | 26.9 (19.6 to 34.2) |
| Time from hospitalisation to death, days | 9.2±6.7 | 10.1±7.7 | 8.9±6.4 | 1.2 (−0.8 to 3.2) |
| Time from symptoms onset to death, days | 15.0±7.9 | 16.2±8.6 | 14.7±7.7 | 1.5 (−0.8 to 3.9) |
ARDS, acute respiratory distress syndrome; CAD, coronary artery disease; CPAP, continuous positive airway pressure; PaO2, arterial oxygen partial pressure.