Table 3

Amalgamated study data cross referencing mitral regurgitation (MR) prevalence, interscallop separation (ISS) and World Heart Federation (WHF) screen-positive disease

Low-risk cohort
(n=359)
High-risk cohort
(n=400)
Total (n/%)*
(n=759)
All ISS cases(n/%)†269 (74.9)278 (69.5)547 (72)
ISS-related MR (n/%)†55 (15.3)49 (12.3)104 (13.7)
ISS-related ‘pathological’ MR (n/%)†11(3)11 (2.8)22 (2.9)
All cases with any MR (n/%)†103 (28.7)100(25)203 (26.7)
MR screening ≥1.5 cm (n/%)†19 (5.3)23 (5.8)42 (5.5)
WHF pathological MR (n/%)†14 (3.9)13 (0.25)27 (3.6)
WHF ‘screen-positive’ cases (n/%)†14 (3.9)13 (3.3)27 (3.6)
WHF ‘borderline RHD’ (n/%)†14 (3.9)11 (2.8)25 (3.3)
WHF ‘definite RHD’ (n/%)†0 (0)2 (0.5)2 (0.3)
  • *Calculated as a percentage of the total enrolled participants.

  • †Calculated as a percentage of the respective cohort.

  • MR, mitral regurgitation; RHD, rheumatic heart disease.