Table 3

Comparison of COVID-19 positive ST-segment elevation myocardial infarction (STEMI) versus COVID-19 negative STEMI: baseline demographic characteristics, primary percutaneous coronary intervention (PPCI) pathway characteristics and admission blood tests

COVID-19 positive
(n=46)
COVID-19 negative
(n=302)
P valueOR (95% CI)
Baseline demographic characteristics
 Age (years)63 (58–67)63 (55–72)0.66
 Male sex37 (80.4%)241 (79.8%)0.66
 Diabetes15 (32.6%)71 (23.5%)0.18
 Hypertension25 (54%)153 (50.7%)0.64
 Hyperlipidaemia24 (52.2%)100 (33.1%)0.012*
 Smoking19 (41.3%)126 (41.7%)0.96
 Previous myocardial infarction5 (10.9%)38 (12.6%)0.74
 Stroke1 (2.2%)10 (3.3%)0.68
 Previous PCI1 (2.2%)40 (13.3%)0.03*
 Previous CABG0 (0%)4 (1.3%)0.43
 Peripheral vascular disease2 (4.4%)8 (2.7%)0.52
 Renal disease1 (2.2%)10 (3.3%)0.68
 Family history of IHD7 (15.2%)34 (11.3%)0.44
Admission blood tests
 Haemoglobin (g/L)137 (116–151)141 (129–152)0.15
 Lymphocytes (×109/L)1.3 (0.88–1.7)1.6 (1.2–2.2)0.003*
 Aspartate aminotransferase (IU/L)66 (33–217)86 (30–231)0.74
 Alanine transaminase (IU/L)46 (32–65)32 (22–59)0.087
 Ferritin (µg/L)427 (213–1529)176 (93–313)<0.001*
 C reactive protein (mg/L)28 (3–122)5 (3–23)0.002*
 Creatinine (µmol/L)83 (68–96)81 (68–98)0.66
 High-sensitivity troponin T (ng/L)749 (174–2617)419 (83–2260)0.18
PPCI pathway characteristics
 Pain—First call (min)103 (30–410)80 (30–331)0.44
 First call—Door (min)88 (68–144)86 (60–114)0.21
 Door—Balloon (min)51 (39–77)47 (32–63)0.026*
 Total ischaemic time (min)360 (223–1418)257 (172–580)0.008*
 Out of hospital cardiac arrest5 (10.9%)33 (10.9%)0.990.99 (0.40 to 2.69)
  • Baseline demographic characteristics, admission blood tests, PPCI pathway timings of patients with STEMI and concurrent COVID-19 and those without COVID-19 admitted during the study periods in 2020.

  • CABG, coronary artery bypass grafting; IHD, ischaemic heart disease.