Number of patients | BB | CCB | P value | ||
26 | 26 | ||||
Positive Ach-induced spasm | |||||
Intention-to-treat analysis | 26.9% | 7 | 26.9% | 7 | 1 |
Per-protocol analysis | 35% | 7 | 31.8% | 7 | 0.21 |
Coronary angiographic findings | |||||
75% spasm | 8% | 2 | 4% | 1 | 0.71 |
90% spasm | 15% | 4 | 15% | 4 | |
99% spasm | 23% | 6 | 27% | 7 | |
100% spasm | 4% | 1 | 0% | 0 | |
QCA | 3.25 | 19.5 | 0.04 | ||
Improvement with nitroglycerin administration | 46% | 12 | 42% | 11 | 0.34 |
Chest discomfort | 42% | 11 | 46% | 12 | 0.27 |
Typical chest discomfort during test | 27% | 7 | 27% | 7 | 0.89 |
Time required for symptom alleviation (minutes) | |||||
Under 5 | 42% | 11 | 58% | 15 | 0.48 |
Above 5 | 23% | 6 | 4% | 1 | |
Ambiguous or unknown | 35% | 9 | 27% | 7 | |
ECG change during provocation | 46% | 12 | 27% | 7 | 0.18 |
Non-specific STT change | 0% | 0 | 8% | 2 | 0.23 |
ST elevation >0.5 mm | 15% | 4 | 8% | 2 | |
ST depression >0.5 mm | 31% | 8 | 15% | 4 | |
Time required for ECG recovery (minutes) | |||||
Under 5 | 31% | 8 | 19% | 5 | 0.54 |
Above 5 | 15% | 4 | 8% | 2 |
Values are mean_SD or n (%).
Ach, acetylcholine; BB, beta blocker; CCB, calcium channel blocker; QCA, quantitative coronary analysis.