Table 6

Clinical outcomes for patients with schizophrenia following an acute myocardial infarction compared with patients without schizophrenia at 5 years

Unadjusted HR (95% CI)Adjusted HR (95% CI)
Model 1Model 2Model 3
MACE1.35 (1.23 to 1.47)*2.44 (2.23 to 2.67)*2.20 (1.79 to 2.72)*2.05 (1.63 to 2.58)*
Mortality1.44 (1.31 to 1.59)*2.99 (2.72 to 3.29)*2.53 (1.00 to 3.21)*2.38 (1.84 to 3.09)*
Reinfarction1.00 (0.82 to 1.24)1.53 (1.25 to 1.89)*1.41 (0.86 to 2.30)1.29 (0.77 to 2.13)
Stroke1.03 (0.80 to 1.34)1.67 (1.29 to 2.17)*1.72 (1.00 to 2.97)1.72 (1.00 to 2.98)
Heart failure1.25 (1.10 to 1.42)*2.14 (1.88 to 2.42)*1.49 (1.13 to 1.98)*1.39 (1.04 to 1.86)*
Bleeding1.09 (0.86 to 1.37)1.55 (1.23 to 1.95)*1.35 (0.85 to 2.14)1.27 (0.79 to 2.05)

  • Model 1: adjusted for age and sex.

  • Model 2: adjusted for age, sex, smoking, comorbidities, previous CAG and previous PCI.

  • Model 3: adjusted for age, sex, smoking, comorbidities, previous CAG and previous PCI, discharge medications and treatment with CAG and PCI.

  • *p<0.005.

  • CAG, coronary angiography; MACE, major adverse cardiac outcome (all-cause mortality, rehospitalisation for AMI, hospitalisation for stroke or heart failure); PCI, percutaneous coronary intervention.