n=103 | Baseline assessment | Follow-up | P value | |
Clinical characteristics | Age | 83.6±3.0 (83.0–84.1) | ||
Female | 33 (32.0%) | |||
BMI | 27.3±4.0 (26.5–28.1) | |||
h/o Hypertension | 64 (62.1%) | |||
h/o Diabetes | 25 (24.8%) | |||
h/o Previous MI | 46 (44.7%) | |||
h/o CKD | ||||
Creat clearance >85 | 7 (6.8%) | |||
Creat clearance 50–85 | 45 (43.7%) | |||
Creat clearance <50 | 50 (48.5%) | |||
Coronary angiography (n=59) | Single-vessel disease | 12 (20.3%) | ||
Two-vessel disease | 24 (40.7%) | |||
Three-vessel disease | 23 (39.0%) | |||
LV function (n=79) | LVEF ≥55 | 43 (54.4%) | ||
LVEF 46%–54% | 18 (22.8%) | |||
LVEF 36%–45% | 13 (16.5%) | |||
Severe LVEF ≤35% | 5 (6.3%) | |||
CCS angina class | No chest pain | 7 (6.8%) | 61 (59.2%) | <0.001 |
CCS class I | 15 (14.6%) | 17 (16.5%) | ||
CCS class II | 33 (32.0%) | 20 (19.4%) | ||
CCS class III | 32 (31.1%) | 5 (4.9%) | ||
CCS class IV | 16 (15.5%) | 0 (0.0%) | ||
NYHA class | NYHA class I | 6 (5.8%) | 17 (16.5%) | 0.05 |
NYHA class II | 64 (62.1%) | 55 (53.4%) | ||
NYHA class III | 29 (28.2%) | 27 (26.2%) | ||
NYHA class IV | 4 (3.9%) | 4 (3.9%) | ||
Fried frailty phenotype | Not frail | 13 (12.6%) | 19 (18.5%) | 0.56 |
Pre-frail | 62 (60.2%) | 54 (52.4%) | ||
Frail | 28 (27.2%) | 30 (29.1%) | ||
Edmonton frailty score | Not frail | 60 (58.3%) | 60 (58.3%) | 0.66 |
Vulnerable | 17 (16.5%) | 19 (18.4%) | ||
Mild frailty | 15 (14.6%) | 16 (15.5%) | ||
Moderate frailty | 8 (7.8%) | 4 (3.9%) | ||
Severe frailty | 3 (2.9%) | 4 (3.9%) | ||
SF-12 physical composite score | 37.2±11.0 | 38.5±11.3 | 0.27 | |
Physical health composite score | At or above | 27 (26.2%) | 33 (32.0%) | 0.19 |
Below | 13 (12.6%) | 13 (12.6%) | ||
Far below | 63 (61.2%) | 56 (54.4%) | ||
SF-12 mental composite score | 52.7±11.5 | 55.1±10.6 | 0.04 | |
Mental health composite score | At or above | 81 (78.6%) | 84 (81.6%) | 0.19 |
Below | 4 (3.9%) | 7 (6.8%) | ||
Far below | 18 (17.5%) | 11 (10.7%) |
BMI, body mass index; CCS, Canadian Cardiovascular Society; CKD, chronic kidney disease; h/o, history of; LVEF, left ventricle ejection fraction; MI, myocardial infarction; NYHA, New York Heart Association.