Table 3

Characteristics of patients with discordant aortic stenosis characterised as either severe or non-severe

Severe (123)Non-severe (160)P value
Age, years76.4 (70.4 to 83.7)73.1 (63.5 to 80.1)<0.001
Sex, % male (n)49.6% (61)45.0% (72)0.44
BMI, kg/m227.8 (24.2 to 32.9)28.4 (24.9 to 33.8)0.66
AVA, cm20.77 (0.63 to 0.86)0.90 (0.77 to 0.96)<0.001
AVAi, cm2/m20.40 (0.33 to 0.45)0.45 (0.40 to 0.51)<0.001
Vmax, m/s3.58 (3.28 to 3.79)3.44 (3.24 to 3.63)0.004
Mean gradient, mm Hg29.7 (25.5 to 33.1)27.0 (23.8 to 31.0)<0.001
Peak gradient, mm Hg51.8 (43.0 to 57.2)47.3 (42.0 to 52.8)0.003
DI0.22 (0.19 to 0.26)0.26 (0.23 to 0.30)<0.001
Ejection fraction, %55 (38 to 60)55 (55 to 61)<0.001
SV, mL61.1 (50.6 to 73.7)71.2 (60.2 to 80.0)<0.001
Indexed SV, mL/m232.5 (26.1 to 38.2)37.5 (30.7 to 42.8)<0.001
LVOT diameter, cm2.02 (2.00 to 2.27)2.00 (2.00 to 2.20)0.20
LVIDd, cm4.59 (3.98 to 5.03)4.32 (3.93 to 4.80)<0.001
LVIDs, cm3.17 (2.60 to 3.84)2.90 (2.50 to 3.30)<0.001
BSA, m21.93 (1.72 to 2.10)1.90 (1.73 to 2.06)0.72
  • Data presented as median (25th percentile, 75th percentile) except where otherwise noted. 7 severe and 4 non-severe patients did not have reliable BMIs recorded, giving n=116‚ÄČand 156 for this metric, respectively. 3 severe and 2 non-severe patients did not have LVID metrics, giving n=120‚ÄČand 158, respectively.

  • AVA, aortic valve area; AVAi, indexed AVA; BMI, body mass index; BSA, body surface area; DI, dimensionless index; LVID, left ventricular internal dimension; LVIDd, LVID in diastole; LVIDs, LVID in systole; LVOT, left ventricle outflow tract; SV, stroke volume; Vmax, peak jet velocity.