All (807) | Female (355) | Male (452) | P value | |
Age, years | 73.7 (65.7 to 80.9) | 75.1 (67.0 to 82.5) | 72.9 (64.9 to 79.9) | 0.03 |
BMI, kg/m2 | 28.8 (25.3 to 33.8) | 29.3 (24.8 to 35.8) | 28.4 (25.6 to 32.6) | 0.04 |
AVA, cm2 | 0.86 (0.70 to 1.00) | 0.80 (0.65 to 0.94) | 0.90 (0.75 to 1.03) | <0.001 |
AVAi, cm2/m2 | 0.43 (0.36 to 0.51) | 0.44 (0.36 to 0.52) | 0.43 (0.36 to 0.50) | 0.09 |
Vmax, m/s | 3.87 (3.41 to 4.38) | 3.80 (3.37 to 4.30) | 3.92 (3.45 to 4.41) | 0.02 |
Mean gradient, mm Hg | 35.0 (26.7 to 45.3) | 33.0 (26.0 to 43.1) | 36.0 (27.5 to 46.0) | 0.01 |
Peak gradient, mm Hg | 59.9 (46.7 to 76.9) | 57.8 (45.3 to 74.0) | 61.2 (47.7 to 78.3) | 0.03 |
DI | 0.24 (0.20 to 0.29) | 0.26 (0.21 to 0.30) | 0.23 (0.20 to 0.28) | <0.001 |
Ejection fraction, % | 55 (55 to 63) | 58 (55 to 63) | 55 (55 to 60) | <0.001 |
SV, mL | 78.1 (64.6 to 90.4) | 73.1 (58.9 to 84.6) | 81.8 (70.2 to 94.1) | <0.001 |
Indexed SV, mL/m2 | 39.7 (32.9 to 46.3) | 39.9 (33.2 to 47.3) | 39.4 (32.8 to 45.6) | 0.22 |
LVOT diameter, cm | 2.10 (2.00 to 2.29) | 2.00 (1.90 to 2.00) | 2.20 (2.10 to 2.30) | <0.001 |
LVIDd, cm | 4.42 (3.90 to 4.90) | 4.10 (3.69 to 4.60) | 4.61 (4.22 to 5.09) | <0.001 |
LVIDs, cm | 2.90 (2.50 to 3.46) | 2.66 (2.31 to 3.10) | 3.17 (2.76 to 3.62) | <0.001 |
BSA, m2 | 1.97 (1.77 to 2.15) | 1.78 (1.64 to 1.96) | 2.08 (1.93 to 2.23) | <0.001 |
Data presented as median (25th percentile, 75th percentile). 11 female and 16 male patients did not have reliable BMIs recorded, giving n=344 and 436 for this metric, respectively. 9 female and 5 male patients did not have LVID metrics, giving n=346 and 447, respectively.
AVA, aortic valve area; AVAi, indexed AVA; BMI, body mass index; BSA, body surface area; DI, dimensionless index; LVID, left ventricular internal dimension; LVIDd, LVID in diastole; LVIDs, LVID in systole; LVOT, left ventricle outflow tract; SV, stroke volume; Vmax, peak jet velocity.