| A: Patient characteristics | ||||
| All patients n=173 | No AF n=139 | AF n=34 | P value | |
| Age* | 33 (17–49) | 26 (14–40) | 56 (46–66) | <0.001 |
| Female | 120(69.4%) | 98 (70.5%) | 22 (64.7%) | 0.511 |
| ASD type | 0.085 | |||
| Ostium primum | 47 (27.2%) | 42 (30.2%) | 5 (14.7%) | |
| Ostium secundum | 124 (71.7%) | 96 (69.1%) | 28 (82.4%) | |
| Sinus venosus | 2 (1.2%) | 1 (0.7%) | 1 (2.9%) | |
| Closure | ||||
| Closed† | 126 (72.8%) | 104 (74.8%) | 22 (64.7%) | 0.235 |
| Surgical | 90 (52.0%) | 74 (53.2%) | 16 (47.1%) | |
| Percutaneous | 36 (20.8%) | 30 (21.6%) | 6 (17.6%) | 0.882‡ |
| Hypertension | 46 (26.6%) | 27 (19.4%) | 19 (55.9%) | <0.001 |
| Diabetes mellitus | 10 (5.8%) | 7 (5.0%) | 3 (8.8%) | 0.415 |
| Obstructive sleep apnoea | 8 (4.6%) | 4 (2.9%) | 4 (11.8%) | 0.049 |
| Left atrial dilatation | 64 (37.0%) | 39 (28.1%) | 25 (73.5%) | <0.001 |
| Cardiac reoperation | 14 (8.1%) | 11 (7.9%) | 3 (8.8%) | 1 |
| Table 1B: Factors associated with atrial fibrillation in univariable and multivariable analyses | |||
| Univariable analyses | OR | 95% CI | P value |
| Age, per year | 1.088 | 1.057 to 1.120 | <0.001 |
| Hypertension | 5.254 | 2.369 to 11.656 | <0.001 |
| Obstructive sleep apnoea | 4.500 | 1.065 to 19.017 | 0.041 |
| Left atrial dilatation | 7.123 | 3.053 to 16.614 | <0.001 |
| Multivariable analysis | |||
| Age, per year | 1.072 | 1.040 to 1.106 | <0.001 |
| Left atrial dilatation | 3.727 | 1.396 to 9.951 | 0.009 |
Values expressed as n (%) or as median (IQR).
*Age at opening of the database (01.01.2004).
†Evaluated at end of our follow period, without regard to when AF was first diagnosed.
‡P value comparing method of closure on the outcome of AF in the closed patients.
ASD, atrial septal defect; AF, atrial fibrillation.