Characteristics and outcome according to the type of surgery (mitral valve repair or replacement) and associated surgery (isolated or combined) (A) in the subset of patients with degenerative mitral regurgitation and (B) in the subset of patients with functional mitral regurgitation
| Isolated mitral valve surgery | Combined mitral valve surgery | |||||||
| Overall | Repair | Replacement | P value | Overall | Repair | Replacement | P value | |
| Degenerative mitral regurgitation | ||||||||
| Number of patients | 5302 | 3810 | 1492 | 2291 | 1380 | 911 | ||
| Age | 65±12 | 63±12 | 68±12 | <0.0001 | 69±11 | 68±11 | 69±11 | 0.14 |
| Male gender | 3193 (60) | 2566 (67) | 627 (42) | <0.0001 | 1342 (59) | 963 (70) | 379 (42) | <0.0001 |
| Charlson Comorbidity Index | 0.71±1.24 | 0.60±1.13 | 1.00±1.43 | <0.0001 | 1.09±1.53 | 1.01±1.45 | 1.22±1.64 | 0.006 |
| Charlson Comorbidity Index ≥2 | 841 (16) | 494 (13) | 347 (23) | <0.0001 | 613 (27) | 333 (24) | 280 (31) | 0.0005 |
| Public hospital | 3196 (60) | 2342 (61) | 854 (57) | 0.005 | 1552 (68) | 960 (70) | 592 (65) | 0.02 |
| Length of stay, total | 13±8 | 12±6 | 15±11 | <0.0001 | 16±10 | 14±9 | 18±11 | <0.0001 |
| Length of stay, intensive care unit | 6±9 | 5±6 | 8±9 | <0.0001 | 8±8 | 7±8 | 9±9 | <0.0001 |
| In-hospital mortality | 129 (2.4) | 43 (1.1) | 86 (5.8) | <0.0001 | 129 (5.6) | 42 (3.0) | 87 (9.6) | <0.0001 |
| Functional mitral regurgitation | ||||||||
| Number of patients | 1431 | 463 | 968 | 1504 | 678 | 826 | ||
| Age | 66±12 | 65±12 | 67±12 | 0.0006 | 68±11 | 69±10 | 68±11 | <0.05 |
| Male gender | 741 (52) | 314 (68) | 427 (44) | <0.0001 | 921 (61) | 509 (75) | 412 (50) | <0.0001 |
| Charlson Comorbidity Index | 1.70±1.98 | 1.59±1.79 | 1.75±2.06 | 0.29 | 2.31±2.28 | 2.37±2.19 | 2.26±2.34 | 0.09 |
| Charlson Comorbidity Index ≥2 | 612 (43) | 184 (40) | 428 (44) | 0.11 | 831 (55) | 396 (58) | 435 (53) | 0.03 |
| Public hospital | 1152 (81) | 587 (84) | 765 (79) | 0.04 | 1191 (79) | 557 (82) | 634 (77) | 0.01 |
| Length of stay, total | 18±15 | 13±8 | 20±17 | <0.0001 | 20±16 | 17±14 | 21±17 | <0.0001 |
| Length of stay, intensive care unit | 9±13 | 5±5 | 11±15 | <0.0001 | 10±13 | 5±12 | 12±14 | <0.0001 |
| In-hospital mortality | 79 (5.5) | 10 (2.2) | 69 (7.1) | <0.0001 | 150 (9.8) | 47 (6.9) | 103 (12.5) | 0.0004 |