Demographics and clinical characteristics of women with INOCA with and without history of HDP
| Characteristics | History of a HDP | P value | |
| No (n=278) | Yes (n=68) | ||
| Demographics | |||
| Age, years | 55.6±10.6 | 53.1±9.6 | 0.05 |
| BMI, kg/m2 | 27.4±6.6 | 31.7±7.5 | <0.001 |
| Race/ethnicity | 0.7 | ||
| White/Non-Hispanic | 207 (74.5%) | 52 (76.5%) | |
| Black/African–American | 20 (7.2%) | 7 (10.3%) | |
| Hispanic/Latin | 24 (8.6%) | 4 (5.9%) | |
| Annual income | 0.04 | ||
| US$0–US$49 000 | 84 (31.2%) | 32 (48.5%) | |
| US$50 000–US$99 000 | 71 (26.4%) | 12 (18.2%) | |
| US$100 000+ | 114 (42.4%) | 22 (33.3%) | |
| Clinical characteristics | |||
| HTN | 92 (35.3%) | 41 (65.1%) | 0.002* |
| Dyslipidaemia | 42 (18.9%) | 11 (22%) | 0.7 |
| Diabetes mellitus | 30 (11%) | 12 (18.2%) | 0.1 |
| Ever smoker | 115 (41.4%) | 25 (37.3%) | 0.6 |
| Cardiovascular medications | |||
| ACE-I or ARB | 65 (24.6%) | 22 (32.8%) | 0.2 |
| Beta blocker | 83 (31.1%) | 27 (40.3%) | 0.2 |
| Calcium channel blocker | 58 (21.9%) | 19 (28.8%) | 0.3 |
| Diuretic | 34 (12.7%) | 14 (20.9%) | 0.1 |
| Postmenopausal | 202 (72.7%) | 52 (76.5%) | 0.6 |
| Number of pregnancies | 3±2, 3 | 4±1, 4 | 0.01 |
| Coronary severity score | 9.2±4.2, 8.5 | 10.3±4.5, 9.6 | 0.1 |
| Angiographic findings | 0.8 | ||
| No CAD | 12 (6.4%) | 4 (8.3%) | |
| No obstructive CAD | 164 (87.2%) | 40 (83.3%) | |
Values are N (%), mean±SD, median (range).
No CAD defined as <20% coronary artery stenosis, no obstructive CAD defined as 20%–50% coronary artery stenosis.
Bold indicates significant p value </= 0.05
*Adjusted for age, BMI, diabetes, annual income, number of pregnancies.
ACE-I, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; BMI, body mass index; CAD, coronary artery disease; HDP, hypertensive disorders of pregnancy; HTN, hypertension; INOCA, ischaemia with no obstructive coronary artery disease.