Table 3

Discrimination of each predicting models for cardiovascular-cause and all-cause mortality using C-index, net reclassification improvement (NRI) and integrated discrimination improvement (IDI)

	C-index (95% CI)	P value	NRI	P value	IDI	P value
CVD-cause mortality
Established risk*	0.630 (0.562 to 0.698)	Reference		Reference		Reference
+GNRI	0.694 (0.635 to 0.754)	0.0026	0.493	<0.0001	0.029	<0.0001
+CRP	0.678 (0.611 to 0.745)	0.0053	0.364	0.0011	0.021	0.017
+GNRI and CRP	0.718 (0.659 to 0.776)	0.0002	0.510	<0.0001	0.056	<0.0001
All-cause mortality
Established risk*	0.648 (0.596 to 0.699)	Reference		Reference		Reference
+GNRI	0.707 (0.660 to 0.754)	0.0036	0.510	<0.0001	0.060	<0.0001
+CRP	0.687 (0.637 to 0.736)	0.0018	0.360	<0.0001	0.031	<0.0001
+GNRI and CRP	0.724 (0.678 to 0.770)	0.0002	0.539	<0.0001	0.081	<0.0001

*Including age, multivessel disease and LVEF as covariates with p<0.05 by univariate analysis.
CRP, C reactive protein; CVD, cardiovascular disease; GNRI, Geriatric Nutritional Risk Index ; LVEF, left ventricular ejection fraction.