Table 2

Predictive value of GNRI and CRP for cardiovascular-cause and all-cause mortality

Non-adjustedAdjusted*
HR (95%CI)P valueHR (95%CI)P value
CVD-cause mortality
GNRI (vs T3)<0.00010.0009
 T21.61 (0.96 to 2.77)0.0731.67 (0.94 to 3.12)0.081
 T12.95 (1.82 to 3.87)<0.00012.45 (1.39 to 4.54)0.0015
 GNRI (continuous)0.94 (0.92 to 0.96)<0.00010.96 (0.94 to 0.98)<0.0001
CRP (vs T1)<0.00010.0009
 T21.44 (0.89 to 2.37)0.131.58 (0.89 to 2.84)0.11
 T32.56 (1.63 to 4.11)<0.00012.98 (1.77 to 5.22)<0.0001
 Log CRP2.09 (1.57 to 2.77)<0.00011.83 (1.37 to 2.43)<0.0001
All-cause mortality
GNRI (vs T3)<0.00010.0001
 T21.58 (1.07 to 2.36)0.0191.54 (1.01 to 2.42)0.048
 T12.99 (2.09 to 4.39)<0.00012.40 (1.58 to 3.74)<0.0001
GNRI (continuous)0.95 (0.93 to 0.96)<0.00010.96 (0.94 to 0.98)<0.0001
CRP (vs T1)<0.0001<0.0001
 T21.53 (1.07 to 2.20)0.0181.39 (0.93 to 2.10)0.10
 T32.46 (1.76 to 3.49)<0.00012.31 (1.58 to 3.43)<0.0001
 Log CRP1.89 (1.53 to 2.33)<0.00011.68 (1.35 to 2.08)<0.0001
  • *Adjusted for age, multivessel disease and LVEF as covariates with p<0.05 by univariate analysis.

  • CRP, C reactive protein; CVD, cardiovascular disease; GNRI, Geriatric Nutritional Risk Index; LVEF, left ventricular ejection fraction.