Table 1

Baseline characteristics

Baseline characteristicsLow-dose opioids
N=115
Intermediate-dose opioids
N=190
High-dose opioids
N=117
P value
Age in years, mean (SD)67 (12)62 (12)59 (11)<0.001
Male, n (%)80 (70)149 (78)107 (92)<0.001
Diabetes, n (%)18 (16)27 (14)24 (21)0.34
Hypertension, n (%)73 (64)103 (54)65 (56)0.263
Dyslipidaemia, n (%)60 (52)97 (51)72 (62)0.175
BMI (IQR; n=271)26.3 (24–30)27.7 (25–30)28 (26–36)0.014
Current or ex-smoking, n (%) (N=419)70 (62)136 (72)88 (75)0.069
PVD, n (%)5 (4)6 (3)3 (3)0.74
CVD, n (%)9 (8)9 (5)6 (5)0.504
IHD, n (%)21 (18)26 (14)30 (26)0.031
Previous PCI, n (%)8 (7)16 (8)25 (21)0.001
Previous CABGs, n (%)5 (4)2 (1)00.024
CCF, n (%)3 (3)5 (3)3 (3)0.999
Creatinine >120 µmol/L, n (%), N=4218 (7)13 (7)11 (9)0.688
Prehospital duration in minutes (IQR), N=40650 (42–61)54 (47–65)64 (53–73)<0.001
Triage time in minutes (IQR),
N=401
2 (1–5)3 (2–5)3 (2–5)0.290
Symptom to intervention time,
N=406
172 (126–311)148 (122–199)165 (129–213)0.181
  • N denotes total sample size (or sample size within groups)

  • n denotes numbers within each characteristic for each group

  • BMI, body mass index; CABG, coronary artery bypass graft surgery; CCF, congestive cardiac failure; CVD, cerebrovascular disease; IHD, ischaemic heart disease; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease.