Table 2

The correlation between %changes of (%Δ) markers during hospitalisation

Entire cohortPIIINP at dischargeP4NP 7S at discharge%ΔPIIINP%ΔP4NP 7S
ValueLowHighP valueLowHighP valueCoefficientP valueCoefficientP value
%ΔT-Bil−20.0%−20.0%−20.0%0.84−16.7%−22.2%0.015−0.110.0430.090.091
%ΔAST−20.8%−26.9%−12.5%0.0001−25.0%−15.4%0.00260.070.190.030.51
%ΔALP−6.9%−8.9%−4.0%0.051−11.3%−1.3%<0.00010.26<0.00010.110.038
%Δγ−GTP−9.7%−16.3%−1.5%<0.0001−11.2%−5.7%0.0120.160.00860.070.22
%ΔAlbumin2.6%5.0%0.0%0.00013.1%0.0%0.011−0.170.003−0.010.78
%ΔeGFR−7.1%−4.3%−10.3%0.005−9.4%−4.7%0.0037−0.130.0240.070.1862
%ΔBNP−56.7%−58.8%−54.6%0.62−66.4%−47.8%<0.0001−0.030.590.31<0.0001
%ΔPIIINP−1.5%−9.9%7.2%<0.0001−4.7%2.4%0.038N/A0.160.0047
%ΔP4NP 7S−15.6%−16.9%−13.5%0.045−20.7%−8.2%<0.00010.160.0047N/A
  • ALP, alkaline phosphatase; AST, aspartate aminotransferase; BNP, brain natriuretic peptide; eGFR, estimated glomerular filtration rate; γ-GTP, γ-glutamyltransferase; PIIINP, N-terminal propeptide of procollagen type III; P4NP 7S, 7S domain of the collagen type IV N-terminal propeptide; T-Bil, total bilirubin.