Baseline characteristics of the study population (n=13 810)
| Variable | Total (n=13 810) | FHx of MI with HF (n=470) | FHx of MI without HF (n=3439) | No FHx (n=9901) | P value |
| Sex, male, n (%) | 10 344 (74.9) | 350 (74.5) | 2662 (77.4) | 7332 (74.1) | <0.001 |
| MI age, mean (SD) | 42.8 (5.7) | 44.6 (4.2) | 43.8 (4.9) | 42.4 (6.0) | <0.0001 |
| Age group (years), n (%) | |||||
| 18–35 | 1649 (11.9) | 23 (4.9) | 254 (7.4) | 1372 (13.9) | <0.0001 |
| 36–50 | 12 161 (88.1) | 447 (95.1) | 3185 (92.6) | 8529 (86.1) | |
| Calendar year, n (%) | |||||
| 1997–2001 | 2316 (16.8) | 76 (16.2) | 567 (16.5) | 1673 (16.9) | 0.977 |
| 2002–2006 | 3924 (28.4) | 135 (28.7) | 964 (28.0) | 2825 (28.5) | |
| 2007–2011 | 3838 (27.8) | 131 (27.9) | 976 (28.4) | 2731 (27.6) | |
| 2012–2016 | 3732 (27.0) | 128 (27.2) | 932 (27.1) | 2672 (27.0) | |
| HT, n (%) | 2637 (19.1) | 113 (24.0) | 733 (21.3) | 1791 (18.1) | <0.0001 |
| Statin use, n (%) | 1848 (13.4) | 96 (20.4) | 589 (17.1) | 1163 (11.7) | <0.0001 |
| DM, n (%) | 1214 (8.8) | 55 (11.7) | 329 (9.6) | 830 (8.4) | 0.008 |
| Kidney disease, n (%) | 441 (3.2) | 13 (2.8) | 101 (2.9) | 327 (3.3) | 0.499 |
| AF, n (%) | 239 (1.7) | 4 (0.9) | 46 (1.3) | 189 (1.9) | 0.029 |
| PVD, n (%) | 215 (1.6) | 7 (1.5) | 65 (1.9) | 143 (1.4) | 0.190 |
| Valve disease, n (%) | 152 (1.1) | 7 (1.5) | 33 (1.0) | 112 (1.1) | 0.505 |
AF, atrial fibrillation; DM, diabetes; FHx, family history; HT, hypertension; MI, myocardial infarction; PVD, peripheral vascular disease.