Table 4

Description of treatment expectations by the patients (PACT-Q1 items) in cohort B (patients newly initiated on dabigatran or a VKA) in the main analysis set

PACT-Q1 itemMissingNot at allA littleModeratelyA lotExtremely
A1—How confident are you that your anticoagulant treatment will prevent blood clots?
 Dabigatran*103 (3.2)46 (1.4)230 (7.2)803 (25.3)1480 (46.6)517 (16.3)
 VKA†64 (2.9)32 (1.5)215 (9.8)701 (32.1)946 (43.3)228 (10.4)
 Overall‡167 (3.1)78 (1.5)445 (8.3)1504 (28.0)2426 (45.2)745 (13.9)
A2—Do you expect that your anticoagulant treatment will relieve some of the symptoms you experience?
 Dabigatran*103 (3.2)361 (11.4)607 (19.1)944 (29.7)911 (28.7)253 (8.0)
 VKA†64 (2.9)261 (11.9)488 (22.3)670 (30.6)599 (27.4)104 (4.8)
 Overall‡167 (3.1)622 (11.6)1095 (20.4)1614 (30.1)1510 (28.1)357 (6.7)
A3—Do you expect that your anticoagulant treatment will cause side effects such as minor bruises or bleeding?
 Dabigatran*103 (3.2)487 (15.3)1201 (37.8)1012 (31.8)320 (10.1)56 (1.8)
 VKA†64 (2.9)250 (11.4)812 (37.1)772 (35.3)253 (11.6)35 (1.6)
 Overall‡167 (3.1)737 (13.7)2013 (37.5)1784 (33.3)573 (10.7)91 (1.7)
A4—How important is it for you to have an anticoagulant treatment that is easy to take?
 Dabigatran*103 (3.2)63 (2.0)106 (3.3)333 (10.5)1676 (52.7)898 (28.2)
 VKA†64 (2.9)32 (1.5)123 (5.6)417 (19.1)1153 (52.7)397 (18.2)
 Overall‡167 (3.1)95 (1.8)229 (4.3)750 (14.0)2829 (52.7)1295 (24.1)
A5—How concerned are you about making mistakes when taking your anticoagulant treatment?
 Dabigatran*103 (3.2)575 (18.1)698 (22.0)767 (24.1)804 (25.3)232 (7.3)
 VKA†64 (2.9)208 (9.5)491 (22.5)646 (29.6)607 (27.8)170 (7.8)
 Overall‡167 (3.1)783 (14.6)1189 (22.2)1413 (26.3)1411 (26.3)402 (7.5)
A6—How important is it for you to take care of your anticoagulant treatment by yourself?
 Dabigatran*103 (3.2)68 (2.1)157 (4.9)398 (12.5)1599 (50.3)854 (26.9)
 VKA†64 (2.9)48 (2.2)139 (6.4)456 (20.9)1097 (50.2)382 (17.5)
 Overall‡167 (3.1)116 (2.2)296 (5.5)854 (15.9)2696 (50.3)1236 (23.0)
A7—How concerned are you about how much you may have to pay for your anticoagulant treatment?
 Dabigatran*103 (3.2)398 (12.5)495 (15.6)1057 (33.2)780 (24.5)346 (10.9)
 VKA†64 (2.9)183 (8.4)186 (8.5)396 (18.1)824 (37.7)533 (24.4)
 Overall‡167 (3.1)581 (10.8)681 (12.7)1453 (27.1)1604 (29.9)879 (16.4)
  • All data are n (%).

  • *Dabigatran: n=3179.

  • †VKA: n=2186.

  • ‡Total: n=5365.

  • PACT-Q, Perception on Anticoagulant Treatment Questionnaire; VKA, vitamin K antagonist.