Table 4

Logistic regression analysis examining the relation of proteins with prevalent atrial fibrillation

	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
	Model 1	P value	Model 2	P value	Model 3	P value
NT-proBNP	4.24 (3.37 to 5.33)	3.56×10^–35	4.38 (3.42 to 5.61)	9.81×10^–32	3.83 (2.93 to 5.02)	1.71×10^–22
PON3	0.65 (0.54 to 0.78)	2.75×10^–6	0.66 (0.55 to 0.80)	1.16×10^–5	0.68 (0.55 to 0.84)	3.15×10^–4
TNFR1	1.11 (0.90 to 1.35)	0.324	0.95 (0.77 to 1.18)	0.658	0.80 (0.63 to 1.00)	0.050
IGFBP-7	1.49 (1.22 to 1.83)	1.24×10^–4	1.37 (1.11 to 1.68)	0.003	1.21 (0.96 to 1.51)	0.102
FABP4	1.51 (1.23 to 1.86)	8.73×10^–5	1.49 (1.19 to 1.87)	0.001	1.17 (0.90 to 1.53)	0.247
OPN	1.38 (1.11 to 1.71)	0.004	1.23 (0.99 to 1.54)	0.065	1.13 (0.90 to 1.43)	0.300
MMP-2	1.33 (1.07 to 1.66)	0.011	1.20 (0.96 to 1.50)	0.110	1.10 (0.87 to 1.40)	0.420
GAL-4	1.38 (1.11 to 1.71)	0.003	1.23 (0.98 to 1.53)	0.068	0.95 (0.74 to 1.21)	0.661
UPAR	1.30 (1.05 to 1.60)	0.014	1.13 (0.91 to 1.41)	0.267	0.95 (0.75 to 1.21)	0.672
GDF-15	1.51 (1.24 to 1.85)	4.73×10^–5	1.27 (1.02 to 1.58)	0.033	1.03 (0.80 to 1.33)	0.813
CHI3L1	1.21 (0.99 to 1.48)	0.066	1.07 (0.87 to 1.33)	0.505	0.99 (0.79 to 1.24)	0.931

Values are ORs and 95% CI for prevalent atrial fibrillation. Model 1 is unadjusted. Model 2 is age and sex adjusted. Model 3 is further adjusted for body mass index, systolic blood pressure, smoking status, prevalent diabetes mellitus, prevalent coronary events, prevalent heart failure and antihypertensive treatment.
CHI3L1, chitinase-3-like protein 1; FABP4, fatty-acid binding protein 4; GAL-4, galectin 4; GDF-15, growth differentiation factor 15; IGFBP-7, insulin-like growth factor-binding protein 7; MMP-2, matrix metalloproteinase-2; NT-proBNP, N-terminal pro-B-type natriuretic peptide; OPN, osteopontin; PON3, paraoxonase 3; TNFR1, tumour necrosis factor receptor 1; UPAR, urokinase receptor.