Clinical characteristics of patients in the derivation and validation cohorts
| Derivation cohort | Validation cohort | |||||
| NSTE-TS (n=100) | NSTEMI (n=100) | P value | NSTE-TS (n=40) | NSTEMI (n=70) | P value | |
| Age (years), mean±SD | 63.6±11.3 | 62.1±12.2 | 0.36 | 61.1±12.0 | 62.6±12.5 | 0.55 |
| Hypertension | 42 (42.0) | 57 (57.0) | 0.03 | 13 (32.5) | 21 (30.0) | 0.78 |
| Dyslipidaemia | 36 (36.0) | 42 (42.0) | 0.38 | 10 (25.0) | 26 (37.1) | 0.19 |
| Diabetes | 12 (12.0) | 31 (31.0) | 0.0011 | 12 (30.0) | 29 (41.4) | 0.23 |
| Current smoker | 13 (13.0) | 19 (19.0) | 0.51 | 5 (12.5) | 17 (24.3) | 0.14 |
| Stress | 70 (70.0) | 15 (15.0) | <0.0001 | 26 (65.0) | 9 (12.9) | <0.0001 |
| Prior CVD | 4 (4.0) | 29 (29.0) | <0.0001 | 3 (7.5) | 27 (38.6) | 0.0004 |
| ST depression in any lead on admission | 1 (1.0) | 20 (20.0) | <0.0001 | 6 (15) | 23 (32.9) | <0.0001 |
| ST depression in any lead on day 1 post-admission | 2 (2.0) | 11 (11.0) | 0.01 | 1 (2.5) | 24 (34.3) | <0.0001 |
| TWI >6 leads on admission | 14 (14.0) | 0 (0) | 0.0001 | 6 (15) | 8 (11) | 0.0005 |
| TWI >6 leads on day 1 post-admission | 57 (57.0) | 10 (10.0) | <0.0001 | 27 (67.5) | 14 (20) | <0.0001 |
Values are n (%) unless otherwise stated.
CVD, cardiovascular disease; NSTEMI, non-ST segment elevation myocardial infarction; NSTE-TS, takotsubo syndrome with non-ST-segment elevation; TWI, T-wave inversion.